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Direct linkPaloyelis, Yannis; Rijsdijk, Fruhling; Wood, Alexis C.; Asherson, Philip; Kuntsi, Jonna – Journal of Abnormal Child Psychology, 2010
Previous studies have documented the primarily genetic aetiology for the stronger phenotypic covariance between reading disability and ADHD inattention symptoms, compared to hyperactivity-impulsivity symptoms. In this study, we examined to what extent this covariation could be attributed to "generalist genes" shared with general cognitive ability…
Descriptors: Reading Difficulties, Conceptual Tempo, Structural Equation Models, Attention Deficit Hyperactivity Disorder
Liu, Xinmin; Akula, Nirmala; Skup, Martha; Brotman, Melissa A.; Leibenluft, Ellen; McMahon, Francis J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Functional magnetic resonance imaging is commonly used to characterize brain activity underlying a variety of psychiatric disorders. A previous functional magnetic resonance imaging study found that amygdala activation during a face-processing task differed between pediatric patients with bipolar disorder (BD) and healthy controls. We…
Descriptors: Quality Control, Adolescents, Patients, Genetics
Utari, Agustini; Chonchaiya, Weerasak; Rivera, Susan M.; Schneider, Andrea; Hagerman, Randi J.; Faradz, Sultana M. H.; Ethell, Iryna M.; Nguyen, Danh V. – American Journal on Intellectual and Developmental Disabilities, 2010
Minocycline can rescue the dendritic spine and synaptic structural abnormalities in the fragile X knock-out mouse. This is a review and preliminary survey to document side effects and potential outcome measures for minocycline use in the treatment of individuals with fragile X syndrome. We surveyed 50 patients with fragile X syndrome who received…
Descriptors: Behavior Disorders, Patients, Drug Therapy, Genetic Disorders
Leventer, Richard J.; Jansen, Anna; Pilz, Daniela T.; Stoodley, Neil; Marini, Carla; Dubeau, Francois; Malone, Jodie; Mitchell, L. Anne; Mandelstam, Simone; Scheffer, Ingrid E.; Berkovic, Samuel F.; Andermann, Frederick; Andermann, Eva; Guerrini, Renzo; Dobyns, William B. – Brain, 2010
Polymicrogyria is one of the most common malformations of cortical development and is associated with a variety of clinical sequelae including epilepsy, intellectual disability, motor dysfunction and speech disturbance. It has heterogeneous clinical manifestations and imaging patterns, yet large cohort data defining the clinical and imaging…
Descriptors: Age, Epilepsy, Mental Retardation, Seizures
Boutwell, Brian B.; Beaver, Kevin M. – Journal of Research in Crime and Delinquency, 2010
There is a vast line of literature showing that antisocial behaviors and personality traits are transmitted across generational lines. Given the ascendancy of Gottfredson and Hirschi's general theory of crime, it is somewhat surprising that no research has examined whether levels of self-control are passed from parent to child. The authors examine…
Descriptors: Personality Traits, Risk, Marriage, Antisocial Behavior
Ronald, Angelica; Happe, Francesca; Dworzynski, Katharina; Bolton, Patrick; Plomin, Robert – Child Development, 2010
Prenatal and neonatal events were reported by parents of 13,690 eighteen-month-old twins enrolled in the Twins Early Development Study, a representative community sample born in England and Wales. At ages 7-8, parents and teachers completed questionnaires on social and nonsocial autistic-like features and parents completed the Childhood Asperger…
Descriptors: Twins, Asperger Syndrome, Questionnaires, Foreign Countries
Uebel, Henrik; Albrecht, Bjorn; Asherson, Philip; Borger, Norbert A.; Butler, Louise; Chen, Wai; Christiansen, Hanna; Heise, Alexander; Kuntsi, Jonna; Schafer, Ulrike; Andreou, Penny; Manor, Iris; Marco, Rafaela; Miranda, Ana; Mulligan, Aisling; Oades, Robert D.; van der Meere, Jaap; Faraone, Stephen V.; Rothenberger, Aribert; Banaschewski, Tobias – Journal of Child Psychology and Psychiatry, 2010
Background: Attention-deficit hyperactivity disorder (ADHD) is one of the most common and highly heritable child psychiatric disorders. There is strong evidence that children with ADHD show slower and more variable responses in tasks such as Go/Nogo tapping aspects of executive functions like sustained attention and response control which may be…
Descriptors: Siblings, Attention Deficit Hyperactivity Disorder, Genetics, Cognitive Processes
Schmitz, Marcelo; Ludwig, Henrique; Rohde, Luis A. – Journal of Clinical Child and Adolescent Psychology, 2010
The objective of the current study was to evaluate a proposed restrictive inattentive type of Attention Deficit Hyperactivity Disorder (ADHD) by comparing clinical correlates among youths with ADHD inattentive type (ADHD-I) as a function of the number of hyperactivity symptoms presented (none vs. 3 or less) and controls (individuals without ADHD).…
Descriptors: Genetics, Attention Deficit Hyperactivity Disorder, Foreign Countries, Control Groups
Pierpont, Elizabeth I.; Weismer, Susan Ellis; Roberts, Amy E.; Tworog-Dube, Erica; Pierpont, Mary Ella; Mendelsohn, Nancy J.; Seidenberg, Mark S. – Journal of Speech, Language, and Hearing Research, 2010
Purpose: This study presents an analysis of language skills in individuals with Noonan syndrome (NS), an autosomal dominant genetic disorder. We investigated whether the language impairments affecting some individuals arise from deficits specifically within the linguistic system or whether they are associated with cognitive, perceptual, and motor…
Descriptors: Genetic Disorders, Congenital Impairments, Children, Adolescents
Ellington, Roni; Wachira, James; Nkwanta, Asamoah – CBE - Life Sciences Education, 2010
The focus of this Research Experience for Undergraduates (REU) project was on RNA secondary structure prediction by using a lattice walk approach. The lattice walk approach is a combinatorial and computational biology method used to enumerate possible secondary structures and predict RNA secondary structure from RNA sequences. The method uses…
Descriptors: Genetics, Prediction, Microbiology, Epilepsy
Gericke, Niklas Markus; Hagberg, Mariana – Science & Education, 2010
This paper explores conceptual variation in the depiction of gene function in upper secondary school textbooks. Historically, concepts in genetics have developed in various scientific frameworks, which has led to a level of incommensurability as concepts have changed over time within their respective frameworks. Since students may have…
Descriptors: Concept Mapping, Textbook Content, Textbooks, Genetics
Sullivan, Heather I. – Bulletin of Science, Technology & Society, 2010
While nature is often claimed to be a space of harmonized balance or an antidote to the chaos of the modern world, we need a more grounded assessment of nature as endlessly changing and much less predictable than we like to assume. In this essay, I explore Karen Traviss' provocative exploration of unbalanced nature and unbounded bodies in her…
Descriptors: Ecology, Physical Environment, Genetics, Influence of Technology
Whose Deaf Genes Are They Anyway?: The Deaf Community's Challenge to Legislation on Embryo Selection
Emery, Steven D.; Middleton, Anna; Turner, Graham H. – Sign Language Studies, 2010
This article centers on the implications of genetic developments (as a scientific and technological discipline) for those Deaf people who identify as a cultural and linguistic minority group and are concerned with the preservation and development of sign language and Deaf culture. We explore the impact of one particular legislative initiative that…
Descriptors: Language Minorities, Sign Language, Deafness, Genetics
Download full textBraun, Michael; Buyer, Regine; Randler, Christoph – International Journal of Environmental and Science Education, 2010
"Non-native organisms are a major threat to biodiversity". This statement is often made by biologists, but general conclusions cannot be drawn easily because of contradictory evidence. To introduce pupils aged 11-14 years to this topic, we employed an educational program dealing with non-native animals in Central Europe. The pupils took…
Descriptors: Foreign Countries, Biodiversity, Outdoor Education, Field Trips
Vuoksimaa, Eero; Kaprio, Jaakko – Psychological Bulletin, 2010
The lack of sex difference in left-handedness in Scandinavian countries reported by Papadatou-Pastou, Martin, Munafo, and Jones (2008) is questioned. We investigated the sex difference in left-handedness in two Finnish, one Norwegian, and one Swedish population-based sample not included in the Papadatou-Pastou et al. (2008) meta-analysis. The…
Descriptors: Handedness, Twins, Foreign Countries, Gender Differences
