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Direct linkAnand, Vibha – ProQuest LLC, 2010
Biomedical research has produced vast amounts of new information in the last decade but has been slow to find its use in clinical applications. Data from disparate sources such as genetic studies and summary data from published literature have been amassed, but there is a significant gap, primarily due to a lack of normative methods, in combining…
Descriptors: Diseases, Genetics, Biomedicine, Organizations (Groups)
Peer reviewedDiaz, Jose Luis – International Social Science Journal, 2010
Bioethics is concerned with the moral aspects of biology and medicine. The bioethical relevance of aggression and violence is clear, as very different moral and legal responsibilities may apply depending on whether aggression and violence are forms of behaviour that are innate or acquired, deliberate or automatic or not, or understandable and…
Descriptors: Child Development, Biology, Natural Sciences, Legal Responsibility
Mick, Eric; Todorov, Alexandre; Smalley, Susan; Hu, Xiaolan; Loo, Sandra; Todd, Richard D.; Biederman, Joseph; Byrne, Deirdre; Dechairo, Bryan; Guiney, Allan; McCracken, James; McGough, James; Nelson, Stanley F.; Reiersen, Angela M.; Wilens, Timothy E.; Wozniak, Janet; Neale, Benjamin M.; Faraone, Stephen V. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Genes likely play a substantial role in the etiology of attention-deficit/hyperactivity disorder (ADHD). However, the genetic architecture of the disorder is unknown, and prior genome-wide association studies (GWAS) have not identified a genome-wide significant association. We have conducted a third, independent, multisite GWAS of…
Descriptors: Evidence, Attention Deficit Hyperactivity Disorder, Quality Control, Genetics
Hall, Scott S.; Lightbody, Amy A.; Hirt, Melissa; Rezvani, Ava; Reiss, Allan L. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Many investigators now routinely classify children with fragile X syndrome (FXS) according to whether or not they also meet diagnostic criteria for autism. To determine whether this classification is appropriate, we examined the profiles of autistic behaviors shown by boys and girls with FXS. Method: Individuals with FXS, aged 5 to 25…
Descriptors: Genetic Disorders, Mental Retardation, Congenital Impairments, Autism
Fontaine, Nathalie M. G.; Rijsdijk, Fruhling V.; McCrory, Eamon J. P.; Viding, Essi – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: To investigate the longitudinal development of callous-unemotional traits (CU) in middle childhood using developmental trajectory analyses in a large twin dataset and examine the degree to which genetic and environmental influences contributed to the CU trajectory-group membership in children. Method: The study included 9,462 youths…
Descriptors: Group Membership, Twins, Females, Early Adolescents
Antshel, Kevin M.; Shprintzen, Robert; Fremont, Wanda; Higgins, Anne Marie; Faraone, Stephen V.; Kates, Wendy R. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: To predict prodromal psychosis in adolescents with velocardiofacial syndrome (VCFS). Method: A total of 70 youth with VCFS, 27 siblings of youth with VCFS, and 25 community controls were followed from childhood (mean age = 11.8 years) into mid-adolescence (mean age = 15.0 years). Psychological tests measuring intelligence, academic…
Descriptors: Children, Adolescents, Congenital Impairments, Genetic Disorders
Valkenburg, Abraham J.; van Dijk, Monique; de Klein, Annelies; van den Anker, Johannes N.; Tibboel, Dick – Developmental Disabilities Research Reviews, 2010
The primary focus of pain research in intellectually disabled individuals is still on pain assessment. Several observational pain assessment scales are available, each with its own characteristics, its own target group and its own validated use. Observational studies report differences in the treatment of intra- and postoperative pain of…
Descriptors: Pain, Down Syndrome, Mental Retardation, Outcomes of Treatment
Hogan, Alexandra M.; Virues-Ortega, Javier; Botti, Ana Baya; Bucks, Romola; Holloway, John W.; Rose-Zerilli, Matthew J.; Palmer, Lyle J.; Webster, Rebecca J.; Baldeweg, Torsten; Kirkham, Fenella J. – Developmental Science, 2010
Millions of people currently live at altitudes in excess of 2500 metres, where oxygen supply is limited, but very little is known about the development of brain and behavioural function under such hypoxic conditions. We describe the physiological, cognitive and behavioural profile of a large cohort of infants (6-12 months), children (6-10 years)…
Descriptors: Ethnicity, American Indians, Adolescents, Foreign Countries
Sanderson, Aimee – Teaching Science, 2010
With new technologies developing so fast, it is difficult for students and teachers alike to keep up to date. Add into the mix skewed media reporting, some creative science fiction films and the unregulated world of the internet, and it becomes increasingly hard to separate fact from fiction. As Australia's largest funding body for stem cell…
Descriptors: Foreign Countries, Ethics, Science Instruction, Genetics
Jittivadhna, Karnyupha; Ruenwongsa, Pintip; Panijpan, Bhinyo – Biochemistry and Molecular Biology Education, 2010
Textbook illustrations of 3D biopolymers on printed paper, regardless of how detailed and colorful, suffer from its two-dimensionality. For beginners, computer screen display of skeletal models of biopolymers and their animation usually does not provide the at-a-glance 3D perception and details, which can be done by good hand-held models. Here, we…
Descriptors: Visual Aids, Models, Genetics, Science Instruction
Birnbaum, Mark J.; Picco, Jenna; Clements, Meghan; Witwicka, Hanna; Yang, Meiheng; Hoey, Margaret T.; Odgren, Paul R. – Biochemistry and Molecular Biology Education, 2010
A key goal of molecular/cell biology/biotechnology is to identify essential genes in virtually every physiological process to uncover basic mechanisms of cell function and to establish potential targets of drug therapy combating human disease. This article describes a semester-long, project-oriented molecular/cellular/biotechnology laboratory…
Descriptors: Cytology, Biotechnology, Molecular Biology, Genetics
Childs-Disney, Jessica L.; Kauffmann, Andrew D.; Poplawski, Shane G.; Lysiak, Daniel R.; Stewart, Robert J.; Arcadi, Jane K.; Dinan, Frank J. – Journal of Chemical Education, 2010
In 1990, a woman was wrongly convicted of poisoning her infant son and was sentenced to life in prison. Her conviction was based on laboratory work that wrongly identified ethylene glycol as present in her son's blood and in the formula he drank prior to his death. The actual cause of the infant's death, a metabolic disease, was eventually…
Descriptors: Biochemistry, College Science, Undergraduate Students, Science Instruction
Erickson, Keith A.; Franciszkowicz, Marc J. – PRIMUS, 2010
A modified version of this project was used during the final seven days of a year-long calculus sequence at the United States Military Academy to introduce students to the nature of integrative learning. Students from different majors were brought together in groups and spent the first few days going over the mathematics material presented here.…
Descriptors: Majors (Students), Genetics, Biology, Mathematics Materials
Grosse, Scott D. – Child Development, 2010
Individuals with late-treated phenylketonuria (PKU) not detected by newborn screening but who followed dietary treatment for at least 12 months before 7 years of age have intelligence quotient (IQ) scores that range from severe impairment to the low-normal range. Among adults with late-treated PKU in California, 85% of those who were born from…
Descriptors: Cognitive Tests, Intelligence Quotient, Mental Retardation, Infants
Geary, David C. – Learning and Individual Differences, 2010
The collection of articles in this special issue and related studies over the past decade provides a fine example of the substantial progress that has been made in our understanding and remediation of mathematical learning disabilities and difficulties since 1993 (Geary, 1993). The originally proposed procedural and retrieval deficits have been…
Descriptors: Mathematics Education, Learning Disabilities, Short Term Memory, Neuropsychology
