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Direct linkHaettig, Jakob; Stefanko, Daniel P.; Multani, Monica L.; Figueroa, Dario X.; McQuown, Susan C.; Wood, Marcelo A. – Learning & Memory, 2011
Transcription of genes required for long-term memory not only involves transcription factors, but also enzymatic protein complexes that modify chromatin structure. Chromatin-modifying enzymes, such as the histone acetyltransferase (HAT) CREB (cyclic-AMP response element binding) binding protein (CBP), are pivotal for the transcriptional regulation…
Descriptors: Inhibition, Brain Hemisphere Functions, Long Term Memory, Spatial Ability
Topcu, Mustafa Sami; Yilmaz-Tuzun, Ozgul; Sadler, Troy D. – Journal of Science Teacher Education, 2011
The purpose of the study is to explore Turkish preservice science teachers' informal reasoning regarding socioscientific issues and the factors influencing their informal reasoning. The researchers engaged 39 preservice science teachers in informal reasoning interview and moral decision-making interview protocols. Of the seven socioscientific…
Descriptors: Qualitative Research, Science Teachers, Climate, Ethics
Exhaustive Analysis of BH4 and Dopamine Biosynthesis Genes in Patients with Dopa-Responsive Dystonia
Clot, Fabienne; Grabli, David; Cazeneuve, Cecile; Roze, Emmanuel; Castelnau, Pierre; Chabrol, Brigitte; Landrieu, Pierre; Nguyen, Karine; Ponsot, Gerard; Abada, Myriem; Doummar, Diane; Damier, Philippe; Gil, Roger; Thobois, Stephane; Ward, Alana J.; Hutchinson, Michael; Toutain, Annick; Picard, Fabienne; Camuzat, Agnes; Fedirko, Estelle; San, Chankannira; Bouteiller, Delphine; LeGuern, Eric; Durr, Alexandra; Vidailhet, Marie; Brice, Alexis – Brain, 2009
Dopa-responsive dystonia is a childhood-onset dystonic disorder, characterized by a dramatic response to low dose of L-Dopa. Dopa-responsive dystonia is mostly caused by autosomal dominant mutations in the "GCH1" gene (GTP cyclohydrolase1) and more rarely by autosomal recessive mutations in the "TH" (tyrosine hydroxylase) or "SPR" (sepiapterin…
Descriptors: Patients, Drug Therapy, Genetic Disorders, Neurological Impairments
Lindahl, Mats Gunnar – Science & Education, 2009
To make meaning of scientific knowledge in such a way that concepts and values of the life-world are not threatened is difficult for students and laymen. Ethics and morals pertaining to the use of genetic tests for hereditary diseases have been investigated and discussed by educators, anthropologists, medical doctors and philosophers giving, at…
Descriptors: Ethics, Moral Values, Genetics, Testing
Thomas, Jacob – ProQuest LLC, 2009
Acyl carrier protein (ACP) is a small essential protein that functions as a carrier of the acyl intermediates of fatty acid synthesis. ACP requires the posttranslational attachment of a 4'phosphopantetheine functional group, derived from CoA, in order to perform its metabolic function. A Mn[superscript 2+] dependent enzymatic activity that removes…
Descriptors: Microbiology, Biochemistry, Genetics
Vaccarino, Flora M.; Grigorenko, Elena L.; Smith, Karen Muller; Stevens, Hanna E. – Journal of Autism and Developmental Disorders, 2009
Increased brain size is common in children with autism spectrum disorders. Here we propose that an increased number of cortical excitatory neurons may underlie the increased brain volume, minicolumn pathology and excessive network excitability, leading to sensory hyper-reactivity and seizures, which are often found in autism. We suggest that…
Descriptors: Autism, Brain, Genetics
Download full textHaibach, Pamela S.; Lieberman, Lauren J. – Journal of Visual Impairment & Blindness, 2013
Introduction: Balance is a critical component of daily living, because it affects all movements and the ability to function independently. Children with CHARGE syndrome have sensory and motor impairments that could negatively affect their balance and postural control. The purpose of the study presented in this article was to assess the balance and…
Descriptors: Visual Impairments, Children, Control Groups, Experimental Groups
Taylor, D. Leland; Campbell, A. Malcolm; Heyer, Laurie J. – American Biology Teacher, 2013
Next-generation sequencing technologies have greatly reduced the cost of sequencing genomes. With the current sequencing technology, a genome is broken into fragments and sequenced, producing millions of "reads." A computer algorithm pieces these reads together in the genome assembly process. PHAST is a set of online modules…
Descriptors: Biology, Information Science, Genetics, Educational Technology
Dyke, Paula; Bourke, Jenny; Llewellyn, Gwynnyth; Leonard, Helen – Journal of Intellectual & Developmental Disability, 2013
Background: The transition from school to adulthood for young adults with an intellectual disability involves movement from a generally secure and supported school environment to an emerging adult life that may be characterised by a wide variation in adoption of adult roles related to employment, independent living, friendships, and day…
Descriptors: Quality of Life, Independent Living, Friendship, Attitude Measures
Cisterna, Dante; Williams, Michelle; Merritt, Joi – American Biology Teacher, 2013
This study explores upper-elementary and early-middle-school students' ideas about cells and inheritance and describes patterns of understanding for these topics. Data came from students' responses to embedded assessments included in a technology-enhanced curriculum designed to help students learn about cells and heredity. Our findings suggest…
Descriptors: Scientific Concepts, Heredity, Teaching Methods, Educational Technology
Poulin, Jessica; Ramamurthy, Bina; Dittmar, Katharina – Journal of College Science Teaching, 2013
Population genetics is fundamental to understanding evolutionary theory, and is taught in most introductory biology/evolution courses. Many students are unaware that understanding this topic requires pertinent knowledge
of mathematics and consequently struggle with the subject. As a response to this problem, a virtual tool (Pop!World) was…
Descriptors: Genetics, Evolution, Learning Modules, Introductory Courses
Norbury, Courtenay Frazier; Sparks, Alison – Developmental Psychology, 2013
Developmental disorders, such as autism spectrum disorder and specific language impairment, are biologically based disorders that currently rely on behaviorally defined criteria for diagnosis and treatment. Specific behaviors that are included in diagnostic frameworks and the point at which individual differences in behavior constitute abnormality…
Descriptors: North Americans, Values, Autism, Language Impairments
Miller, Beverly A. King – ProQuest LLC, 2013
This grounded theory case study examines the experiences of Panamanian Afro-Caribbean women and their membership in STEM (Science, Technology, Engineering and Mathematics) training and careers. The shortage of Science and Math teachers in 48 of 50 States heightens the need for those trained in STEM. Females of African phenotype have persistently…
Descriptors: Females, Interviews, Surveys, Qualitative Research
Eklund, Kenneth Mikael; Torppa, Minna; Lyytinen, Heikki – Dyslexia, 2013
This longitudinal study examined early cognitive risk and protective factors for Grade 2 reading disability (RD). We first examined the reading outcome of 198 children in four developmental cognitive subgroups that were identified in our previous analysis: dysfluent trajectory, declining trajectory, unexpected trajectory and typical trajectory. We…
Descriptors: Reading Difficulties, Cognitive Development, Grade 2, Dyslexia
Tucker-Drob, Elliot M.; Harden, K. Paige – Journal of Child Psychology and Psychiatry, 2013
Background: Preschool involves an array of new social experiences that may impact the development of early externalizing behavior problems over the transition to grade school. Methods: Using longitudinal data from a nationally representative sample of over 600 pairs of US twins, we tested whether the genetic and environmental influences on…
Descriptors: Intelligence, Behavior Problems, Genetics, Etiology
