Histone deacetylase (HDAC) plays a role in synaptic plasticity and long-term memory formation. We hypothesized that trichostatin-A (TSA), an HDAC inhibitor, would promote long-term odor preference memory and maintain enhanced GluA1 receptor levels that have been hypothesized to support memory. We used an early odor preference learning model in…

To examine the interactive effects of two proposed risk factors which may contribute to symptom severity of Autism Spectrum Disorder (ASD): prenatal antidepressant exposure and likely gene-disrupting (LGD) mutations. Participants included 2748 individuals with ASD from the Simons Simplex Collection. We examined the effects of prenatal…

Research in learning progressions (LPs) has been essential towards building understanding of how students' ideas change over time. There has been little work, however, into how ideas between separate but related constructs within a multi-faceted LP relate. The purpose of this paper is to elaborate on the idea of "progression webs" to…

The molecular structure of living organisms and the complex interactions amongst its components are the basis for the diversity observed at the macroscopic level. Proteins and nucleic acids are some of the major molecular components, and play a key role in several biological functions, such as those of development and evolution. This article…

Background: Retrospective parental reports have often been used to identify the early characteristics of children later diagnosed with a developmental disorder. Method: We applied this methodology to document 13 parents' initial concerns about the development of their 17 children later diagnosed with fragile X syndrome (FXS). Parents were…

Creativity is an important twenty-first century skill often overlooked in higher education curricula, particularly in the sciences. Students need opportunities to practice and demonstrate their creativity and gain an awareness of the importance of such skills to enhance their graduate capabilities. One way is to embed creativity into course…

There is a disparity in the number of adults from minority populations employed in STEM careers. In order to increase the interest of at-risk high school students in the STEM field in Queens, NY, an immersive summer biotechnology boot camp was developed. Fifty-five predominantly minority and female students completed the summer boot camp over a…

ADHD is a disability characterised by hyperactivity, impulsivity and difficulties maintaining attention. Despite extensive research on ADHD, the effects of existing treatments are moderate and inconsistent. Knowledge regarding children's and adolescents' everyday experiences of Attention Deficit Hyperactivity Disorder (ADHD) and their…

Background: Advances in medical genetics herald the possibility that health and social care services could be more responsive to the needs arising from a person's genotype. This development may be particularly important for those men and women whose learning disability (known internationally as intellectual disability) is linked to a…

The practice of RNA isolation in undergraduate experimental courses is rare because of the existence of robust, ubiquitous and stable ribonucleases. We reported here modifications to our original protocol for RNA isolation from plant tissues, including the recovery of nucleic acids by ethanol precipitation at 0 degrees C for 10 min and the…

In the present study, we examined the effects of feedback that corrects and contrasts a student's own erroneous solutions with the canonical, correct one (CEC&C feedback) on learning in a conceptual change task. Sixty undergraduate students received expository instruction about natural selection, which presented the canonical, scientifically…

The present study investigates whether grade 6 reading outcomes, reading fluency, and reading comprehension can be predicted by grade 3 reading fluency, familial risk of dyslexia (FR), and grade 3 reading related skills: rapid automatized naming (RAN), phonological awareness (PA), and vocabulary. In a sample of 150 children, of whom 83 had a…

Background: Generating interest in health interventions is an important first step towards engagement with health promotion and effecting behaviour change. This study explored whether framing health information about physical activity and diet from an evolutionary mismatch perspective could help to generate interest in health promotion among…

Problem-based learning (PBL) fosters both content knowledge and content understanding, improves critical and process thinking skills, and promotes peer-to-peer learning, leadership, and teamwork (Hmelo-Silver 2004). Instructors support the PBL process by guiding students through activities that challenge their current knowledge and understanding…

Although engineering design is dependent upon the use of science and mathematics, the actual prototype, model, or solution that pre-college students generate can be accomplished without the students explicitly using scientific or mathematical concepts. It is therefore important to explore how students apply science and mathematics concepts when…