The present study aims to investigate the views of secondary school students on an entrepreneurship-assisted science course. The study was carried out with the case study method, one of the qualitative research methods. The study data were collected with qualitative research techniques such as focus group interviews and diaries. The study group included 23 5th-grade students attending a secondary school located in Adiyaman urban center during the 2020-2021 academic year. The data were analyzed with content analysis. The study findings demonstrated that students considered the entrepreneurship-assisted science course and related practices as fun and interesting in the focus group interviews. Similarly, the diary entries revealed that the entrepreneurship-assisted science course and the activities were enjoyable according to the students and they liked these activities. Furthermore, it should be noted that the students mentioned entrepreneurship dimensions in both focus group interviews and diaries.