The dopamine system has been implicated in decision-making particularly when associated with effortful behavior. We examined acute optogenetic stimulation of dopamine cells in the ventral tegmental area (VTA) as mice engaged in an effort-based decision-making task. Tyrosine hydroxylase-Cre mice were injected with Cre-dependent ChR2 or eYFP control…

Lab activities are characteristic of life science education. In the current study, we investigate whether pre-lab modules can improve students' understanding of the theories and experimental procedures associated with lab activities. Such effects were studied in context of an expository lab on gene mapping in biology undergraduate education. An…

This essay sheds light on the "father of epigenetics," Conrad Hal Waddington's (1905-1975) tacit critique of one of the most prominent biologists of the twentieth century, Julian Huxley's (1887-1975) theses concerning the evolutionary meaning and importance of learning and education for the human species. This topic has great…

Using data from 266 age- and sex-matched pairs of Jamaican children with autism spectrum disorder (ASD) and typically developing (TD) controls (2-8 years), we investigated whether glutathione S-transferase theta 1 ("GSTT1") modifies the association between blood manganese concentrations (BMC) and ASD. After adjusting conditional logistic…

This qualitative study analyses how effective an activity based on the critical and reflexive reading of the historical case of Rosalind Franklin and the elucidation of the molecular structure of DNA can be for learning about the nature of science (NOS). The aspects of NOS addressed are the plurality of methods in scientific research, research…

A plethora of neuroimaging studies have focused on the discovery of potential neuroendophenotypes useful to understand the etiopathogenesis of autism and predict treatment response. Social robotics has recently been proposed as an effective tool to strengthen the current treatments in children with autism. However, the high clinical heterogeneity…

The global learning community, led by researchers in fields such as psychology, sociology and pedagogics, had arrived at a consensus about the social "and" biological nature of learning until work in epigenetics brought new insights. After a brief overview of learning theories and the role of the environment, recent findings from…

Social impairments are common features of 22q11.2 deletion syndrome (22q11DS) and autism spectrum disorders (ASD). The Ecological Momentary Assessment (EMA) allowed access to daily-life information in order to explore the phenomenology of social interactions. 32 individuals with 22q11DS, 26 individuals with ASD and 44 typically developing peers…

Communication deficits have a substantial impact on quality of life for individuals with Angelman syndrome (AS) and their families, but limited qualitative work exists to support the necessary content of measures aiming to assess communication for these individuals. Following best practices for concept elicitation studies, we conducted individual…

This study aims to examine the unique educational films prepared by science teacher candidates about biotechnology applications and getting their perceptions on the process/the educational films they have prepared. The phenomenology method was used. The study group consists of 30 sophomore teacher candidates. Teacher candidates prepared…

Journal clubs are well regarded as a highly effective means of engaging graduate students with the contemporary research literature, where individual students prepare and deliver presentations on selected research articles to their peers, followed by a group discussion. Regular journal clubs have the advantage of enhancing student scientific…

Studies of educational games often treat them as "black boxes" (Black and Wiliam in Phi Delta Kappan 80: 139-48, 1998; Buckley et al. in Int J LearnTechnol 5:166-190, 2010; Buckley et al. in J Sci Educ Technol 13: 23-41, 2010) and measure their effectiveness by exposing a treatment group of students to the game and comparing their…

In instructional settings, evolution and natural selection are challenging concepts to teach, due to the fact that these topics are difficult to observe in the laboratory or lecture hall. In the past few years, Avida-ED has emerged as an innovative tool for teaching evolutionary principles. It allows students to directly observe effects of…

The present study has two main goals. First, it aims to examine the analogies an instructor uses about "DNA conservation across generations" in a university-level General Biology course. Second, it aims to examine the analogies used in those lessons according to Thiele and Treagust's framework. A qualitative case study design is adopted…

Teachers often struggle to facilitate open discussions about evolution when they perceive it to be at odds with cultural and religious norms. Little is understood about classroom discourse and teacher-student interactions during the teaching of evolution. This study analyzed classroom discourse and teacher-student exchanges in a 10th-grade biology…