An efficient synthesis of the exorbitantly priced Lambert-Eaton myasthenic syndrome drug amifampridine was developed and applied in the second-semester undergraduate organic chemistry laboratory. The two-step synthesis entails a nucleophilic aromatic substitution reaction of commercial 4-chloro-3-nitropyridine with methanolic ammonia to afford…

Course based undergraduate research experiences (CUREs) enable students to connect theoretical coursework to the real-world application of scientific research, broadly increasing the accessibility of research to students. Similarly, service-learning courses connect undergraduate students to their surrounding communities by anchoring a component of…

The carbonyl group of an aldehyde or ketone reacts with different types of nucleophiles through a nucleophilic addition reaction. When the nucleophile is water, the product obtained is a "gem"-diol or geminal diol. This functionalization is unstable and quickly reverts to the parent carbonyl group. The chemistry of "gem"-diols…

Nonresponse bias is a widely prevalent problem for data on education. We develop a ten-step exemplar to guide nonresponse bias analysis (NRBA) in cross-sectional studies and apply these steps to the Early Childhood Longitudinal Study, Kindergarten Class of 2010-2011. A key step is the construction of indices of nonresponse bias based on proxy…

The value of high-impact practices in undergraduate higher education is well documented. However, very little is known about high-impact practices in Human Development and Family Science (HDFS) programs. The goal of this study was to explore one specific high-impact practice: undergraduate research. Specifically, our study explored the benefits…

Legitimacy has been used to understand institutional and faculty behaviors within higher education contexts. Faculty members frequently apply the concept of professional legitimacy to their work, such as publishing and teaching. Few studies have considered how legitimacy is enacted when advising undergraduate students about graduate education.…

Study abroad (SA) in North America is changing in two ways: short-term trips are becoming more popular, and more students are traveling in teacher-facilitated groups. These changes raise questions about how teaching methods can help to improve outcomes in short stays abroad, particularly in the case of language learners. To better understand…

Q methodology is a unique, yet underutilized methodology designed specifically to scientifically study subjectivity. Q, as it is most often referred to, is an appropriate methodology whenever a researcher is interested in uncovering and describing the multiple divergent viewpoints on any topic. Such discovery of viewpoints provides insight into…

Research in psychology and education tend to use large-N group designs that necessitate reporting of mean measures analyzed mostly with null hypothesis statistical testing (NHST), but sometimes with Bayesian, or the estimation approaches in inferential statistics. These approaches all render the average person or student as the the putative…

Human bodies vary widely: height, weight, blood volume, handedness, strength, and variations from disabilities, trauma, genetics, etc. Engineers must be trained to include human variance when designing human-interactive systems. Typically, this is not incorporated into mathematical and modeling focused courses. In the spring of 2019, one of three…

Heightened awareness of the impacts of trauma and early life adversities has created a greater interest in the broader applications of trauma-informed practice. Trauma-informed practices in professional and educational organizations are increasingly seen as a critical aspect of equitable learning, creating a need for quality educational…

The aim of this study was to taxonomically analyze the Spring and Summer 2022 Lifeway Bible Studies for Life curriculum for adults. The focus of the study was to determine whether the curriculum successfully engages learners across various learning dimensions, fostering a more holistic and impactful experience, the inquiry is significant not only…

A [beta]-lactam, the core structure unit of clinically important antibiotics such as penicillin and cephalosporin, is one of the most commonly encountered four-membered heterocycles in organic chemistry and is widely used in medicine and biochemistry. The Kinugasa reaction, a copper­(I)-catalyzed cycloaddition of a terminal alkyne with a nitrone,…

During the COVID-19 pandemic, schools rapidly changed from in-class instruction to remote learning. Parent involvement and management of the home learning situation was greatly emphasized, and this presented challenges and opportunities for parents of children with attention-deficit/hyperactivity disorder (ADHD). There was an urgent need for…

In the United States, students often graduate from high school unprepared to succeed in college. In Alabama, fewer than 25% of high school graduates are college ready. Frequently, unprepared students enroll in community colleges, which are tasked to help them transfer to a four-year institution or to enter the workforce. However, students who need…