Background: Coughing and throat clearing are different airway protective manoeuvres elicited in the framework of dysphagia. However, coughing and throat clearing may be auditorily confused during a clinical swallowing evaluation. In addition, literature reporting comparisons between coughing and throat clearing via gold standard airflow metrics is lacking. Aims: To report quantitative airflow data for voluntary throat clearing, and to examine in a healthy population the aerodynamical differences between voluntary throat clearing, voluntary cough and induced reflexive cough. Methods and Procedures: Forty healthy participants were included in the study. Airflow measurements were obtained from single voluntary throat clearings, single voluntary coughs and the first two induced reflexive coughs of the reflexive cough epoch. The measurements included the peak expiratory flow rate in litres/s and the cough expired volume in litres of each single manoeuvre. Outcomes and Results: Results showed that voluntary throat clearing displayed lower airflow feature values compared to voluntary cough and induced reflexive cough (p < 0.001). Conclusions and Implications: Voluntary throat clearings were aerodynamically significantly different from voluntary and reflexive coughs. Future studies should determine whether these differences reflect distinct impacts on airway protection. In dysphagic populations, instrumental assessment of throat clearing may enhance clinical swallowing evaluations.