Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

The process of turning a doctoral student into an independent researcher is usually guided by a professor. In this work, the supervisor-supervisee relationship is represented by a scheme inspired by Michaelis-Menten kinetics, which has been used to determine the rate of enzyme-catalysed reactions. Here, the time evolution of the number of…

Kinetic energy is usually the entry point for the study of energy in physics and is often perceived as unproblematic. We present evidence, however, that some learners who seem to have accepted the concept, from elementary school students to college physics majors and in-service teachers, nevertheless do not consistently attribute kinetic energy to…

The modeling of rates of biochemical reactions--fluxes--in metabolic networks is widely used for both basic biological research and biotechnological applications. A number of different modeling methods have been developed to estimate and predict fluxes, including kinetic and constraint-based (Metabolic Flux Analysis and flux balance analysis)…

The reaction rate and rate law are chemical kinetics concepts that undergraduate students have difficulty understanding and applying in real life. A further challenge is the overall reaction rate of consecutive reactions. Herein we present a creative teaching practice using the analogy-based approach to exploit the similarities between the…

An application for visualizing the dynamic properties of an equimolar binary mixture of isotropic reactive particles is presented. By introducing a user selectable choice for the activation energy, the application is useful to demonstrate qualitatively that the reaction rate depends on the above choice and on temperature. The application is based…

Models that are used to predict and explain phenomena related to molecular vibration and rotation are ubiquitous in physical chemistry, and are of importance in many related fields. Yet, little work has been done to characterize student use and application of these models. We describe the results of a multi-year, multi-institutional qualitative…

Many teachers are confused about how to implement the phenomena-based teaching recommended by the "Next Generation Science Standards" (NGSS Lead States 2013). This article describes one possible approach--purposely repurposing existing activities. This process involves having teachers: (1) Choose a phenomenon that informs the development…

In this article Campbell and Neilson discuss several design strategies developed or adopted that were found particularly helpful when sequencing a unit that focused on learning about motion and acceleration. Students were expected to predict, observe, and explain why a ball traveled down one ramp faster than the other. Before engaging students,…

To familiarize first-year students with the important ingredients of a physics experiment, we offer them a project close to their daily life: measuring the effect of air resistance on a bicycle. Experiments are done with a bicycle freewheeling on a downhill slope. The data are compared with equations of motions corresponding to different models…

The POGIL-PCL project implements the principles of process-oriented, guided-inquiry learning (POGIL) in order to improve student learning in the physical chemistry laboratory (PCL) course. The inquiry-based physical chemistry experiments being developed emphasize modeling of chemical phenomena. In each experiment, students work through at least…

A traditional organic chemistry laboratory experiment involves the acid-catalyzed isomerization of (-)-menthone to (+)-isomenthone. This experiment generates large quantities of organic and aqueous waste, and only allows the final ratio of isomers to be determined. A "green" modification has been developed that replaces the mineral acid…

Elementary, middle-level, and high school science teachers commonly find their students have misconceptions about heat and temperature. Unfortunately, student misconceptions are difficult to modify or change and can prevent students from learning the accurate scientific explanation. In order to improve our students' understanding of heat and…

In this activity, science education and modern technology are bridged to teach students at the high school and undergraduate levels about protein folding and to strengthen their model building skills. Students are guided from a textbook picture of a protein as a rigid crystal structure to a more realistic view: proteins are highly dynamic…

We take another look at the Helmholtz model for the gravitational contraction of the Sun. We show that there are two other pedagogically useful ways of rederiving Helmholtz's main results that make use of Gauss's law, the concept of gravitational field energy and the work-kinetic energy theorem. An account of the energy balance involved in the…