A frequent challenge that graduate and undergraduate students in chemistry, biology, and pharmacy laboratories face is accurately assigning proton and carbon peaks in the 1D and 2D Nuclear Magnetic Resonance (NMR) spectra of organic and pharmaceutical molecules. We propose a consistent, step-by-step approach to effectively assist students in…

Hybridization is a bonding model, universally used in organic chemistry, which allows consideration of two-electron localized bonds in organic molecules. Without hybridization, it is almost impossible to describe aspects such as hyperconjugation for the stabilization of carbocations and alkane conformers. Hybridization is often presented in…

A chemistry laboratory experiment is described to introduce undergraduate college students to membrane separation technology. This experiment combines a simple nanowire membrane fabrication and visually indicated molecule separation. The membrane is produced via coprecipitation synthesis followed by a filtration assembly process, which can be…

A new teaching resource comprised of raw X-ray diffraction data sets from crystallography experiments has been compiled. The aim of this resource is to provide a tool with which to plug the teaching gap between crystals and chemical structures present at various levels of education, as well as providing examples for early stage researchers and…

The COVID-19 pandemic affected a large range of in-person education activities in Colombia. This created great limitations in academic performance for students with reduced access to communication technologies and deepened the educational gaps in the country. This was particularly true for sciences such as biochemistry. In Colombia, molecular…

The great development of high-throughput molecular biology techniques and the consequent generation of massive data have made Bioinformatics essential for undergraduate Bioscience students. The importance of this scientific discipline is evidenced by the huge number of specialized publications, tools, and databases available. Training in…

A strong understanding of molecular structure is key for mastering structure-function concepts in life sciences and is based on the visualization of biomolecules. Therefore, various approaches to help students translate between the 2D space of a textbook figure to the 3D space of a molecule have been developed. Object-based learning is an approach…

Representations in chemistry are the tools by which students, instructors, and chemists reason with chemical concepts that are abstract. Although representations are regularly used within the chemistry classroom, there is more to uncover regarding the ways students interact with representations when given chemistry tasks. This study aimed to…

Resonance is a fundamental chemistry concept first introduced to students in General Chemistry I, reintroduced in Organic Chemistry I, and then utilized throughout other higher-level chemistry courses. A molecule or ion can be said to exhibit resonance when it can be represented by two or more chemical structures (i.e., Lewis structures) that…

The initial learning experience is a critical opportunity to support conceptual understanding of abstract STEM concepts. Although hands-on activities and physical three-dimensional models are beneficial, they are seldom utilized and are replaced increasingly by digital simulations and laboratory exercises presented on touchscreen tablet computers.…

Most chemistry instruction and assessment lie in the symbolic domain of Johnstone's representational levels, despite years of chemistry education researchers calling for increased emphasis to be placed on the molecular or particulate level of chemistry. Without a deep understanding of the particulate nature of matter and molecular-level…

In response to the great challenge that the teaching of basic sciences currently entails in the new generations of young people and seeking to awaken the interest of our students in chemistry and its areas of influence, we developed an innovative card game named "Amino-structure" which served as a key tool to implement an active learning…

Teaching chemistry and biology students about biologics design remains challenging despite its increasing importance in pharmaceutical development. Monoclonal antibodies, commonly called mAbs, are the most popular biologics. They have been developed into drugs to treat various diseases in the past decades. Multiple challenges exist for designing…

Many approaches to teaching Newman projections and conformational manipulation rely on lecturing using only two-dimensional representations. While molecular models are recognized as useful learning tools, students are often left to figure out how to use them during the initial learning process. The availability of basic online molecular models…

Asking students to explain why phenomena occur at a molecular level is vital to increasing their understanding of chemistry concepts. One way to elicit students' mechanistic reasoning and guide construction of knowledge is through Writing-to-Learn (WTL), which is a promising approach for students in organic chemistry courses. In the design of WTL…