Reward is thought to attenuate forgetting through the automatic effect of dopamine on hippocampal memory traces. Here we report a conceptual replication of previous results where we did not observe this effect of reward. Participants encoded eight lists of pictures and recalled picture content immediately or the next day. They were informed that…

Intra-individual response time variability (IIRTV) during cognitive performance is increasingly recognized as an important indicator of attentional control (AC) and related brain region function. However, what determinants contribute to preschoolers' IIRTV received little attention. The present study explored the interaction of dopaminergic…

Some previous studies have shown that increased stress hormone levels have beneficial effects on memory encoding; however, there is no clear consensus on which encoding-related processes are affected by stress hormones. In the present study, we investigated the relationship between interindividual differences in neuroendocrine response to acute…

This paper uses evidence-centered assessment design (ECD) to structure and analyze a laboratory activity where students collect and represent titration curve data to determine acid strength in terms of molarity and dissociation constant. Following principles of multidimensional learning, the activity prompts students to demonstrate knowledge of…

We used a technique known as reach tracking to investigate how individual differences in working memory capacity (WMC) relate to the functioning of two processes proposed to underlie cognitive control: a threshold adjustment process that temporarily inhibits motor output in response to signals of conflict and a controlled selection process that…

Feedback loop reasoning is an essential part of systems thinking, which includes the analysis and description of system behaviour and regulative measures. In feedback loops, every change can simultaneously represent a cause and an effect. Research on reasoning in feedback loops is limited to investigating students' existing mental models. This…

Research shows that alcohol has a small and inconsistent effect on eyewitness recall and no effect on witnesses' lineup decisions. Much of this literature has tested participants with low-to-moderate blood alcohol concentration (BAC) levels, and no study has directly examined how identification procedure impacts intoxicated witnesses' decisions.…

Honeybees are a standard model for the study of appetitive learning and memory. Yet, fewer attempts have been performed to characterize aversive learning and memory in this insect and uncover its molecular underpinnings. Here, we took advantage of the positive phototactic behavior of bees kept away from the hive in a dark environment and…

Students in higher education have been shown to have difficulties in developing their critical thinking skills, such as analysis and problem solving, reasoning and argumentation. Open-ended tasks offer opportunities for students to develop their own interpretations of various sources, to critically analyse domain-specific knowledge and utilize…

In an increasingly complex world, it is imperative that undergraduate science courses prepare students to make confident, informed decisions and predictions. The research presented in this thesis focuses on supporting students to engage in mechanistic reasoning (MR) about phenomena in chemistry and biology (that is, thinking about how and why…

The evolutionarily conserved Elongator Complex associates with RNA polymerase II for transcriptional elongation. Elp3 is the catalytic subunit, contains histone acetyltransferase activity, and is associated with neurodegeneration in humans. Elp1 is a scaffolding subunit and when mutated causes familial dysautonomia. Here, we show that…

Nonprotein coding dendritic BC1 RNA regulates translation of mRNAs in neurons. We examined two lines of BC1 knockout mice and report that loss of BC1 RNA exaggerates group I mGluR-stimulated LTD of the Schaffer collateral synapse, with one of the lines showing a much more enhanced DHPG-induced LTD than the other. When the animals were given the…

The aim of research was validation of a method for the assessment of cognitive complexity of chemical technology problem tasks. The method included an assessment of the difficulty of concepts and an assessment of their interactivity. As a research instrument for assessing performance, test of knowledge was used. Each task in the test was followed…

Phosphorylation of CaMKII and AMPA receptor GluA1 subunit has been shown to play a major role in hippocampal-dependent long-term/reference memory (RM) and in the expression of long-term synaptic potentiation (LTP). In contrast, it has been proposed that dephosphorylation of these proteins could be involved in the opposite phenomenon of hippocampal…

Long-term fear memory formation in the hippocampus and neocortex depends upon brain-derived neurotrophic factor (BDNF) signaling after acquisition. Incremental, appetitive odor discrimination learning is thought to depend substantially on the differentiation of adult-born neurons within the olfactory bulb (OB)--a process that is closely associated…