Background: Mucopolysaccharidosis type III (MPS III) is a rare lysosomal storage disease with systemic complications. This scoping review aimed to synthesise evidence regarding methods to diagnose and monitor MPS III. Methods: We searched 10 databases for English and Spanish citations published from 2017 to 2022. Our study focused on human-based…

Background: We investigated how many individuals with Rett syndrome were undergoing interventions to reduce stereotypic hand movements and the factors determining the presence or absence of an intervention. Method: A questionnaire was sent to 194 families. Each survey item was compared between the intervention and non-intervention groups according…

Background: Adults with intellectual disability, especially those with Down syndrome, are at increased risk of dementia. Whilst memory decline is often considered the earliest symptom, emerging research indicates decline in language, executive function, and non-cognitive domains may also occur early, potentially before memory changes. Method: A…

Background: Social competence training for individuals with comorbid autistic spectrum disorder (ASD) and intellectual disability was scarce and had methodological limitations in sample sizes and outcome measures. Aims: The current study addressed the limitations and reported a social competence intervention for adolescents and adults with ASD and…

Background: Problem behaviours are common among people with intellectual disabilities (ID), but psychometrically evaluated instruments for assessing such behaviours are scarce. The present study evaluated the psychometric properties of the Neuropsychiatric Inventory--Intellectual Disability (NPI-ID). Method: We assessed 108 residents with…

Background: The aim of this study was to investigate the prevalence of and the factors associated with psychiatric symptoms (PS) and challenging behaviour (CB) in adults with intellectual disabilities, and the utilization of psychiatric services in Turkey. Method: Psychiatric Assessment Schedule for Adults with Developmental Disorders…

Background: Previous research has suggested a variety of possible relationships between the presence of symptoms of psychiatric disorder and challenging behaviours in people with intellectual disability. This study explores this relationship in a total population sample of adults with challenging behaviour. Materials and Methods: Over 800 service…

Background: Obsessive-compulsive (O-C) traits, and excessive food intake are well known behavioural manifestations among individuals with Prader-Willi Syndrome (PWS). Other unwanted behaviours are also frequently observed, but they need a more specific investigation, especially in the adult population. Methods: The behaviour of 31 PWS adults was…

Background: Repetitive questions and temper outbursts form part of the behavioural phenotype of Prader-Willi syndrome (PWS). We investigated the phenomenology of temper outbursts in PWS and their relationship with other PWS behavioural characteristics. Method: Four individuals with PWS were observed (5-10 h), during a number of experimental and…

Background: Antipsychotics are the most frequently prescribed psychotropic medication for people with intellectual disabilities. Many people are prescribed this medication for "challenging behaviours" without having had a formal diagnosis of a psychiatric disorder. Antipsychotics have been reported to have severe side-effect profiles, which can…

Background: Childhood sexual and physical abuse has been related to subsequent offending behaviour in non-disabled individuals as well as people with intellectual disabilities, but there is a dearth of research examining the link between these two characteristics and psychological, behavioural and psychiatric symptoms amongst sex offenders with…

Background: The study concerns the unknown value of group instruction for mothers of young children with Down syndrome (DS) in preventing or minimizing sleep problems. Method: (1) Children with DS were randomly allocated to an Instruction group (given basic information about children's sleep) and a Control group for later comparison including…