The context in which reward-paired cues are encountered can resolve ambiguity and set the occasion for appropriate reward-seeking. The psychological processes by which contexts regulate reward-seeking remain unclear as contexts are diffuse and difficult to isolate from other stimuli. To overcome this, we modeled a context as a phasic and discrete…

Study was designed to investigate the effects of signalled non-contingent reward on the operant behaviour of human subjects. (Authors)

This research was supported by Research Grant No. 30-200-50, Indiana University Foundation, Indiana University.

Eight- and 9-year-olds (N=56) were studied to determine the degree to which counterconditioning could alter the positive or negative value acquired by a neutral stimulus in a conditioning situation. Dependent measures used to assess the effects of conditioning were found to have no independent effect on subsequent evaluations of the once-neutral…

Results of numerous human imaging studies and nonhuman neurophysiological studies on "reward" highlight a role for frontal, striatal, and thalamic regions in operant learning. By integrating operant and functional neuroimaging methodologies, the present investigation examined brain activation to two types of discriminative stimuli correlated with…

One symptom of depression is loss of motivation, which can be defined as responsiveness to response-eliciting stimuli and quantified as reward-related behavioral output. Long-term changes in reward-related behavior have been shown to follow early life stress. Most rodent studies investigating the effects of postnatal separation, an early stress,…