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Direct linkMigliavaca, Celina Borges; Stein, Cinara; Colpani, Verônica; Barker, Timothy Hugh; Ziegelmann, Patricia Klarmann; Munn, Zachary; Falavigna, Maicon – Research Synthesis Methods, 2022
Over the last decade, there has been a 10-fold increase in the number of published systematic reviews of prevalence. In meta-analyses of prevalence, the summary estimate represents an average prevalence from included studies. This estimate is truly informative only if there is no substantial heterogeneity among the different contexts being pooled.…
Descriptors: Incidence, Meta Analysis, Statistics, Statistical Distributions
Shi, Jiandong; Luo, Dehui; Weng, Hong; Zeng, Xian-Tao; Lin, Lu; Chu, Haitao; Tong, Tiejun – Research Synthesis Methods, 2020
When reporting the results of clinical studies, some researchers may choose the five-number summary (including the sample median, the first and third quartiles, and the minimum and maximum values) rather than the sample mean and standard deviation (SD), particularly for skewed data. For these studies, when included in a meta-analysis, it is often…
Descriptors: Statistics, Computation, Sample Size, Mathematical Formulas
Yamaguchi, Yusuke; Sakamoto, Wataru; Goto, Masashi; Staessen, Jan A.; Wang, Jiguang; Gueyffier, Francois; Riley, Richard D. – Research Synthesis Methods, 2014
When some trials provide individual patient data (IPD) and the others provide only aggregate data (AD), meta-analysis methods for combining IPD and AD are required. We propose a method that reconstructs the missing IPD for AD trials by a Bayesian sampling procedure and then applies an IPD meta-analysis model to the mixture of simulated IPD and…
Descriptors: Meta Analysis, Patients, Bayesian Statistics, Comparative Analysis
Jackson, Dan – Research Synthesis Methods, 2013
Statistical inference is problematic in the common situation in meta-analysis where the random effects model is fitted to just a handful of studies. In particular, the asymptotic theory of maximum likelihood provides a poor approximation, and Bayesian methods are sensitive to the prior specification. Hence, less efficient, but easily computed and…
Descriptors: Computation, Statistical Analysis, Meta Analysis, Statistical Inference
Verde, Pablo E.; Ohmann, Christian – Research Synthesis Methods, 2015
Researchers may have multiple motivations for combining disparate pieces of evidence in a meta-analysis, such as generalizing experimental results or increasing the power to detect an effect that a single study is not able to detect. However, while in meta-analysis, the main question may be simple, the structure of evidence available to answer it…
Descriptors: Randomized Controlled Trials, Bayesian Statistics, Comparative Analysis, Evidence
Simmonds, Mark C.; Higgins, Julian P. T.; Stewart, Lesley A. – Research Synthesis Methods, 2013
Meta-analysis of time-to-event data has proved difficult in the past because consistent summary statistics often cannot be extracted from published results. The use of individual patient data allows for the re-analysis of each study in a consistent fashion and thus makes meta-analysis of time-to-event data feasible. Time-to-event data can be…
Descriptors: Meta Analysis, Markov Processes, Monte Carlo Methods, Statistics
Glass, Gene V. – Research Synthesis Methods, 2015
The 40-year history of meta-analysis is traced from the vantage point of one of its originators. Research syntheses leading to the first examples of meta-analysis are identified. Early meta-analyses of the literature on psychotherapy outcomes and school class size are recounted. The influence on the development of meta-analysis of several…
Descriptors: Meta Analysis, Research Methodology, Psychotherapy, Class Size
