Chemistry of the environment has been a long-standing and important area of scientific research. Atmospheric chemistry is of particular interest in society due to the impact that rising levels of pollutants are having on the climate. It is well-known that combustion processes create CO and NO[subscript x], which leads to the creation of other…

Ferrocene is an organometallic compound widely incorporated into undergraduate organic and inorganic chemistry curricula. Traditional laboratory experiments typically involve the Friedel-Crafts acylation of ferrocene to produce acetylferrocene or diacetylferrocene, with a purification method focused on column chromatography. To expand the…

In this second-semester organic chemistry lab experiment, students work collaboratively using a combination of chemical synthesis and NMR spectroscopy to investigate the diastereoselectivity associated with the Meerwein-Ponndorf-Verley (MPV) reduction of two ketone substrates having carbonyl groups flanked by an [alpha]-chiral carbon with…

Amides are usually prepared using amines and acyl halides, which often implies a two-step procedure. Alternatively, coupling reagents can be used in a single-step reaction with good yields, which seems to be suitable for organic chemistry laboratory classes. This work was designed to synthesize "N"-hexylcinnamamide through a one-step…

Introductory physics laboratory experiments have typically been employed to reinforce classroom instruction instead of teaching students experimental design. Recent research has shown that lab experiments that focus on experimental practices are more effective at teaching students physics concepts. The experiment described in this paper has been…

The identification of coloring substances is a relevant task in the field of conservation and restoration, but it can be challenging as in real samples the target analytes are inserted in a very complex matrix made of binders and additives. Understanding this concept is fundamental for upper-division undergraduate students interested in…

We report a research-enhanced undergraduate laboratory practical in which students synthesize and characterize color-controllable, stable silver nanoparticles for use in a simple catalytic reaction analyzed by UV-vis spectroscopy. The practical has been prepared for students using electronic laboratory notebooks, enables collaborative data…

Nuclear magnetic resonance (NMR) spectroscopy is an indispensable technique in the organic chemistry laboratory for elucidation of molecular structure. Miniaturization of NMR technology has attracted attention and acceptance due to a considerable reduction in the cost to acquire and maintain the instrument. The advent of low-field, low-cost, and…

Polymerization reaction media can have a profound effect on the physical properties of the resultant polymer. This phenomenon is showcased in a new experiment for the organic chemistry and polymer science teaching laboratories wherein the radical copolymerization of biobased [beta]-myrcene and dibutyl itaconate is performed using a nonhazardous…

High-resolution mass spectrometry (HRMS) is an analytical technique that is typically used by mass spectrometry experts. However, with recent advancements, it is becoming more accessible to students in organic chemistry laboratories. Still, a significant knowledge gap exists between these experts and students. A straightforward laboratory…

The imine condensation reaction is commonly addressed in second semester organic chemistry classrooms as imines and their derivatives are found in many pharmaceutical scaffolds and biological and catalytic processes. Despite this, imine condensations are still absent from many organic chemistry laboratory curriculums. The work discussed here…

Benzoin, an [alpha]-hydroxy ketone, is stereoselectively reduced by sodium borohydride to yield hydrobenzoin, the stereochemistry of which is determined by acetalization and analysis of the derivative by NMR spectroscopy. This classical experiment has been enhanced by modern spectroscopic and computational analysis to enable students to…

This experiment combines analytical techniques of solid-phase extraction (SPE) and gas chromatography quadrupole time-of-flight mass spectrometry (GC-QTOF-MS) to determine organochlorine pesticides (OCPs) in river water as a means to develop and improve student understanding of the use of GC-QTOF-MS for qualitative and quantitative analysis. In…

Short chain fatty acids (SCFAs) are produced in the gut as a result of microbial action on ingested dietary fiber and have been associated with several health benefits. Herein an undergraduate student experiment that uses gas chromatography equipped with either a flame ionization detector or mass spectrometer for the analysis and quantitation of…

In this communication, we describe five at-home laboratory experiments and demonstrations that complement a semester-long analytical chemistry curriculum. The experiments were successfully carried out by remote undergraduate students enrolled in a hybrid analytical chemistry course during the COVID-19 pandemic. Students used their personal…