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Hartel, Aaron M.; Hanna, James M., Jr. – Journal of Chemical Education, 2009
A single-pot procedure for the preparation of methyl salicylate (oil of wintergreen) from commercial aspirin tablets has been developed. The synthesis proceeds via a tandem transesterification-Fischer esterification using acidic methanol and can be carried out using either conventional or microwave heating. The experiment helps demonstrate acyl…
Descriptors: Spectroscopy, Student Interests, Organic Chemistry, Science Instruction

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