Reduction in the expression or function of [alpha]5-subunit-containing GABA[subscript A] receptors ([alpha]5GABA[subscript A]Rs) leads to improvement in several hippocampus-dependent memory domains. However, studies thus far mostly lack anatomical specificity in terms of neuronal circuits and populations. We demonstrate that mice with a selective…

The medial prefrontal cortex (mPFC) is known to be critical for specific forms of long-term recognition memory, however the cellular mechanisms in the mPFC that underpin memory maintenance have not been well characterized. This study examined the importance of phosphorylation of cAMP responsive element binding protein (CREB) in the mPFC for…

Visual Reproduction is a condition to measure Visual Spatial Memory as one of the cognitive domains commonly used to measure visuo-spatial memory. Geometric figures serve as stimulus material, and probands have to reproduce the figures from memory through a hand drawing. The scoring of the drawing has subjective elements. This study aims to…

Background: Recent research suggested fluent processing as an explanation on why number sense contributes to simple arithmetic tasks--'Fluency hypothesis'. Aims: The current study investigates whether number sense contributes to such arithmetic tasks when other cognitive factors are controlled for (including those that mediate the link); and…

We compared two versions of an n-back training program, differing from the graphical perspective, on the effects of working memory (WM) training and transfer. Sixty participants were trained on a traditional n-back task (2D perspective) or an augmented reality (AR) version of the same program. The AR version was rated more engaging and graphically…

Short-term memory (STM) and working memory (WM) capacity, which are at the centre of information processing, are significant predictors of learning in both children with typical hearing (TH) and hearing loss. We compared the performance of long-term cochlear implant (CI) users with their typical hearing (TH) peers on verbal short-term memory…

Previous studies have found that block play results in better spatial ability which may lead to greater mathematical skills. The current study examined a specific type of block play, structured block play in which a copy of a block configuration is constructed. Structured block play is a difficult cognitive task that requires an understanding of…

Semantic similarity between stimuli can lead to false memories and can also potentially cause retroactive interference (RI) for veridical memories. Here, participants first learned spatial locations for "critical" words that reliably produce false memories in the Deese-Roediger-McDermott paradigm. Next, participants centrally viewed…

Developmental dyscalculia (DD) is a mathematics learning disorder that affects approximately 5% to 7% of the population. This study aimed to detect the underlying domain-specific and domain-general differences between DD and typically developing (TD) children. We recruited 9-year-old primary school children to form the DD group via a 2-year…

People's expectations help them make judgments about the world. In the area of spatial memory, the interaction of existing knowledge with incoming information is best illustrated in the category effect, a bias in positioning a target toward the prototypical location of its region (Huttenlocher et al., 1991). According to Bayesian principles, these…

The study identified the cognitive mechanisms that underly individual differences in mathematics and reading. There is little systematic evidence regarding the connections between cognitive capabilities, mathematics and reading among high-school students with typical development. Moreover, the study aimed to examine whether or not gender is…

This research is part of the "Ancient Xuzhou Houses in China: Cultural Memory, Symbol and Process Reconstruction in the Context of Rural Revitalization" project. Traditional houses contain a large amount of cultural value, literacy role, and historical memory. In order to sort out the transfer process more clearly between memory and…

Reports on differences between remembering the past and imagining the future have led to the hypothesis that constructing future events is a more cognitively demanding process. However, factors that influence these increased demands, such as whether the event has been previously constructed and the types of details comprising the event, have…

This study aimed to draw a cross-task comparison on visuospatial processing in autism spectrum disorder without intellectual disability. Participants with autism spectrum disorder were matched with typically developing individuals on general intelligence and perceptual reasoning index. The two groups were subsequently compared on visuospatial…

Working Memory (WM) is an essential concept of cognitive science since many aspects of human learning depend on it. Primarily proposed by Baddeley and Hitch (1974) and developed by Baddeley (1986), the concept of WM comprises the number of subsystems involved during the process and the considerable emphasis on its key role in cognitive tasks such…