The presented research hypothesis-driven laboratory exercise teaches advanced undergraduate students state of the art methods and thinking in an integrated molecular physiology context. Students understand the theoretical background of iron acquisition in the model plant "Arabidopsis thaliana." They design a flowchart summarizing the key…

Carl Erich Correns (1864-1933) is remembered in the annals of science as one of the three botanists who re-discovered Mendel's laws. He can also, however, be regarded as one of the founding figures of classical genetics in Germany. Between 1894 and 1899 he carried out the crossing experiments with corn and peas that led to the re-statement of…

This historical narrative describes the foundation of education as established by J. A. Comenius (1592-1670). It explores the transfer of Comenius' tenets, utilized and modified through the years, up to their impact upon the ground-breaking experiments of G. Mendel (1822-1884), "the father of genetics". It explores the questions of…

Science textbooks and classes mostly emphasize what are considered by today's standards the "right" or "correct" interpretations of particular phenomena or processes. When "incorrect" ideas of the past are mentioned at all, it is simply to point out their errors, with little attention as to why the ideas were put…

"Cootie Genetics" is a hands-on, inquiry-based activity that enables students to learn the Mendelian laws of inheritance and gain an understanding of genetics principles and terminology. The activity begins with two true-breeding Cooties of the same species that exhibit five observable trait differences. Students observe the retention or…

Although the development of next-generation (NextGen) sequencing technologies has revolutionized genomic research and medicine, the incorporation of these topics into the classroom is challenging, given an implied high degree of technical complexity. We developed an easy-to-implement, interactive classroom activity investigating the similarities…

Gel electrophoresis is the single most important molecular biology technique and it is central to life sciences research, but it is often too expensive for the secondary science classroom or homeschoolers. A simple safe low-cost procedure is described here that uses household materials to construct and run DNA gel electrophoresis. Plastic…

Extracting DNA from fruit and vegetables provides students with hands-on opportunities to engage with a visualisation of genetic material that can later be supported by ICT and practical model making. Here is a quick, cheap and easy way to extract DNA from strawberries that avoids the mess involved in other DNA extractions, such as from dried…

It is widely accepted that inquiry-based curriculum programs have positive effects on cognitive achievement, process skills, and attitudes toward science (NRC 2000). Science teachers seek engaging, effective, and inquiry-based activities that are standards-aligned and convenient to implement in their classrooms. For many years, the web has…

This study investigates how high school students respond to an environment of authentic science inquiry while participating in an intensive summer institute, the Waksman Student Scholars Programme at Rutgers University. We examined how students apprenticed with expert scientists in a study of contemporary questions in molecular genetics. Students…

Restriction enzymes are basic tools in recombinant DNA technology. To shape the molecular biology experiments, the students must know how to work with these molecular scissors. Here, we describe an integrated set of experiments, introduced in the "Advances in Molecular Biology and Biotechnology" postgraduate course, which covers the important…

Undergraduate biology programs are currently undergoing reform to involve students in biomedical research. Engaging students in more active, hands-on experiments allows students to discover scientific principles for themselves, and to develop techniques of critical thinking and problem solving. This models the world of real scientific research,…