The function of proteins is governed by their three-dimensional structure. This structure is determined by the chemical characteristics and atomic interactions of amino acids. Students of biochemistry, with a particular focus on protein chemistry, benefit from looking at protein structures and understanding how proteins are built and fold. Due to…

Many approaches to teaching Newman projections and conformational manipulation rely on lecturing using only two-dimensional representations. While molecular models are recognized as useful learning tools, students are often left to figure out how to use them during the initial learning process. The availability of basic online molecular models…

Asking students to explain why phenomena occur at a molecular level is vital to increasing their understanding of chemistry concepts. One way to elicit students' mechanistic reasoning and guide construction of knowledge is through Writing-to-Learn (WTL), which is a promising approach for students in organic chemistry courses. In the design of WTL…

Molecular representations that show chemical bonding are ubiquitous in general and organic chemistry. These help in communicating chemistry concepts that are fundamental to understanding "how" and "why" molecules interact. The goal of this dissertation work is to offer an evidence-based report on the affordances and limitations…

Students perceive molecular bonding as an abstract concept; therefore, learning this concept seems uninteresting and difficult. A strategically designed learning object (LO), such as in the form of a simulation, can be used to help students acquire accurate mental images and build appropriate schema in addition to providing a concrete learning…

Abundant prior research has compared effects of physical and virtual manipulatives on students' conceptual learning. However, most prior research has been based on conceptual salience theory; that is, it has explained mode effects by the manipulative's capability to draw students' attention to conceptually relevant (visual or haptic) features.…

One of the goals of science education is to help students make sense of the world around them. To that end, it is critical that students understand the central ideas in each discipline like, in chemistry, energy and interactions. These ideas are of particular importance because they are directly related to one another and are relevant across other…

Molecular symmetry and orbitals are two important chemical concepts which can be difficult for students to visualize in three dimensions; as such, instructors have traditionally adopted a variety of approaches to teach them including the use of physical models and digital renderings/resources. This paper describes a new mobile device application…

Biology and biochemistry students must learn to visualize and comprehend the complex three-dimensional (3D) structures of macromolecules such as proteins or DNA. However, most tools available for teaching biomolecular structures typically operate in two dimensions. Here, we present protocols and pedagogical approaches for using immersive augmented…

Undergraduate biology students' molecular-level understanding of stochastic (also referred to as random or noisy) processes found in biological systems is often limited to those examples discussed in class. Therefore, students frequently display little ability to accurately transfer their knowledge to other contexts. Furthermore, elaborate tools…

Many undergraduate chemistry students struggle to understand the concept of stereoisomers, molecules that have the same molecular formula and sequence of bonded atoms but are different in how their atoms are oriented in space. Our goal in this study is to improve stereoisomer instruction by getting participants actively involved in the lesson.…

Enzymatic activity is at the core of biological reactions. Understanding them and the chemical and environmental factors that affect reaction rates is critical for biology students. The laboratory experiment proposed here investigated these concepts, while requiring students to document, graph data, analyse results using statistics, and…

Students undertaking courses in the field of chemistry need to integrate their spatial skills and conceptual knowledge. However, model perception along with the understanding of spatial processes and spatial structures of molecules has been a cause of difficulty for students as conventional teaching methods cannot fully aid student comprehension.…

This study aimed to develop pre-service science teachers' conceptual understanding of a nanoscience project through a newly introduced 8E learning cycle. This research was conducted during one semester of a nanoscience and nanotechnology course in the chemistry education department in Universitas Negeri Jakarta, Indonesia with thirty-three…

In an introductory biology course, we implemented a learner-centered, model-based pedagogy that frequently engaged students in building conceptual models to explain how genes determine phenotypes. Model-building tasks were incorporated within case studies and aimed at eliciting students' understanding of 1) the origin of variation in a population…