A renewed experimental procedure for the unknown carbonyl experiment has been developed using hydrazone synthesis, thin layer chromatography (TLC) analysis, and melting point determination to differentiate between structurally similar ketones and aldehydes in undergraduate organic chemistry practical courses. Benzaldehyde, p-tolualdehyde,…

A laboratory experiment was designed to introduce the practical application of biocatalysis in Bachelor and Master courses in biotechnology and medicinal chemistry, respectively. To this aim, the lipase from "Candida rugosa" was characterized (protein concentration and activity), immobilized on a carrier (by hydrophobic adsorption), and…

This paper outlines a comprehensive teaching laboratory course program that centers on titration analysis, a timeless and essential technique in analytical chemistry spanning various disciplines, such as environmental science, medicine, and industry. In these fields, titration analysis is paramount for determining the concentrations of substances…

This communication describes an updated experiment of peptide synthesis, involving determination of the loading capacity of a Fmoc-protected amino functionalized resin using UV-vis spectroscopy and a subsequent synthesis of a dipeptide in order to exemplify the experimental solid-phase synthesis procedure as an alternative technique in organic…

Laboratory work has been a common element of science courses at university level for around two centuries, but its practice has been criticised by scholars in the field and related stakeholders. Mainly on a rationale of financial justification and educational efficacy, more evidence for learning has been called for. The aims of this systematic…

Science labs should promote reasoning that resembles the work that scientists do. However, this is often not the case. We present a lab in which students strive to find out which of two models best describes a physics experiment. The quantification of measurement uncertainties--another topic that is often neglected in high school…

Flow cytometry has become an important tool in the fields of veterinary, medicine, and biological sciences in general. However, in the introductory and even in advanced university degree courses, students do not have many opportunities to be in contact with this type of technology. This situation motivated us to design a simple and inexpensive…

The COVID-19 epidemic adversely impacted chemical engineering experiments(CEEs). Students underwent online learning, i.e., software simulation of the CEE course, instead of laboratory learning. A questionnaire survey revealed that students exhibited low enthusiasm for online learning, showing that online courses cannot ensure learning quality.…

A drug discovery project has been successfully implemented in an advanced undergraduate organic chemistry laboratory. In the laboratory, a five-step synthetic sequence is used to prepare five analogues of 13-phenyl-1-tridecanol. These compounds are key precursors in the synthesis of 2-oxo-14-phenyltetradecanes. This class of compounds, isolated…

The aldol condensation reaction is one of the many synthesis reactions carried out in second semester organic chemistry laboratories. This reaction was integrated into a novel experiment requiring students to synthesize dibenzalace tone derivatives using the crossed-aldol condensation by reacting different types of benzaldehyde derivatives with…

This experiment introduces undergraduate organic chemistry students to analysis and interpretation of Fourier transform infrared (FTIR) spectra through characterization of postconsumer plastics. Students use FTIR spectra to identify and differentiate the common recyclable polymer resins #1-6: polyethylene terephthalate (PETE), polyethylene (HDPE…

Students sometimes learn about a model of the "scientific method" that is linear and clear cut. While this approach may have pedagogical advantages, it does not reflect how science is often done in practice. The Experimental Modeling Framework (EMF) describes the complex and iterative process of experimentation in the domain of physics,…

The teaching of laboratory skills to undergraduate students is central to all experimental sciences. In this setting, students must understand the experimental procedures as well as the fundamental principle(s) being demonstrated, all while learning within a limited time. Other limiting factors include access to equipment and reagents, resulting…

A traditional laboratory course with the primary learning outcome of improving students' theoretical knowledge has received much criticism over the years due to the lack of evidence that these goals have achieved. We report our efforts to redesign a traditional first-year organic and inorganic (also known as synthetic) laboratory course from…

[This paper is part of the Focused Collection on Instructional labs: Improving traditions and new directions.] Research on nontraditional laboratory (lab) activities in physics shows that students often expect to verify predetermined results, as takes place in traditional lab activities. This understanding of what is taking place, or…