Electrophilic aromatic substitution (S[subscript E]Ar) and nucleophilic aromatic substitution (S[subscript N]Ar) reactions are among the most valuable reactions in the conversion of aromatic rings. While these reactions are typically covered in separate experiments in undergraduate organic courses, a continuous experimental setup elucidating both…

Undergraduate students of a molecular cell biology laboratory class learn basic recombinant DNA (rDNA) technology by engaging in a Genomic Library Construction Project. Significantly, in this lab project students learn experimental design strategy. The challenge for students is to determine the strategy that they can take to efficiently screen for…

NMR prediction using ChemDoodle, NMR calculation with Gaussian, and hands-on data collection using a benchtop NMR spectrometer were explored to assess their synergistic capacity in teaching NMR to organic chemistry students. Nine molecules representing functional groups commonly encountered in undergraduate organic chemistry were selected. Spectra…

Removing the pollutants from various wastewater is crucial to the environment, ecology, and humans. However, the pollutants are generally removed by chemical decomposition, which not only consumes a lot of energy but also produces carbon emissions. Electrochemical flocculation is effective to extract pollutant molecules and heavy ions from…

Calculating analytical uncertainties as a part of method validation is a relevant aspect of field and laboratory practices in instrumental analytical chemistry subjects, which usually require complex algorithms. This work describes the development and didactic use of an automatic and straightforward informatics tool, implemented in an Excel macro,…

The chemical experiment in this study is specifically created for undergraduate students studying energy and the environment. The target of the experiment is for students to comprehend the deactivation mechanism of the Ce/TiO[subscript 2] catalyst by oxides of phosphorus through practical experiments and enhance their knowledge of environmental…

We describe a three-day advanced organic laboratory experience that includes the solid-phase synthesis of an unknown three amino acid polypeptide for junior/senior undergraduate chemistry majors. Students conduct a series of 1D and 2D NMR experiments (HSQC, HMBC, TOCSY) and analyze the data to identify the side chain residues of the peptide and…

In this laboratory teaching experiment, commercial cannabis oils were analyzed by undergraduate organic chemistry students using gas chromatography-mass spectrometry (GC-MS) to investigate three isomeric cannabinoids commonly found in cannabis products: cannabidiol (CBD), [delta][superscript 9]-tetrahydrocannabinol ([delta][superscript 9]-THC),…

This paper outlines a comprehensive teaching laboratory course program that centers on titration analysis, a timeless and essential technique in analytical chemistry spanning various disciplines, such as environmental science, medicine, and industry. In these fields, titration analysis is paramount for determining the concentrations of substances…

Quantum dots are colloidal semiconductor nanocrystals that display size-dependent electronic and optical properties. These materials are a visual demonstration of a quantum-mechanical effect. Here we present a laboratory exercise for undergraduate/Bachelor students as an introduction to colloidal nanocrystals and quantum dots. The students…

Providing hands-on practical education without access to laboratories during the COVID-19 pandemic has required creativity and innovation. In this paper, co-authored by academic staff and students, we describe an at-home mobile phone-based 'spectrophotometer' experiment used in an introductory undergraduate biology course. Using colour picker…

By hosting a college students' laboratory skills contest, we provide an interesting activity for students to cultivate good laboratory practices and thereby improve their laboratory skills. The substance of this contest is the detection of the hardness of water, which involves numerous laboratory skills such as solution preparation, weight by…

Using crystal structure data, site directed mutagenesis, and real-time kinetic assays, students designed, expressed, and purified engineered mutants of human insulin-degrading enzyme (IDE). Students designed their own IDE mutants following "in silico" analysis, used inverse PCR to generate mutant plasmid expression constructs, expressed…

Structure--activity relationships are foundational concepts in biochemistry and drug design. Despite their importance, it can be difficult to create and execute laboratory activities that allow students to directly observe the interactions between small-molecule drugs and their biomolecular targets. Here, we report an activity that investigates…

Cycloadditions in combination with multicomponent reactions are among the most valuable synthetic tools used by organic chemists to construct cyclic and heterocyclic compounds in a straightforward way. Although cycloadditions, such as the Diels--Alder reaction, are mainly covered in basic and advanced organic courses for undergraduate students,…