The area of application of electrospray ionization mass spectrometry (ESI-MS), usually coupled with liquid chromatography, seems to be much larger than those of any other ionization method. It gives rise to the demand for new teaching methods that would effectively help students to master the principles of working with and making full use of the…

The concept of co-amorphous systems is introduced in an integrated laboratory experiment, designed for advanced chemistry students, using solvent-free, environmentally friendly mechanochemistry. The dual-drug naproxen-cimetidine co-amorphous system (NPX-CIM) is investigated as an example of the emergent field of medicinal mechanochemistry.…

We have developed a new foundation-level course at our institution that links the concept of chemical equilibria from four of the traditional subdisciplines (analytical, biochemistry, inorganic, and physical). The course, entitled Solution and Solid State Chemistry (CHEM 210), is designed to serve our chemistry and biochemistry majors, as well as…

In an idealized General Chemistry Laboratory curriculum, students would hone their experimental design ability with practice encouraged by laboratory exercises designed to be open-ended. However, traditional General Chemistry Laboratory courses often lack opportunities for students to design their own experiments, instead opting to provide…

In chemistry, a eutectic mixture refers to a mixture of two or more components at which the lowest possible freezing point is observed. This phenomenon is covered in a wide range of curricula such as physics, chemistry, chemical engineering, and pharmacy to various depths. Despite the significance of this phenomenon in pharmaceutical compounding…

Potash, an essential raw material of the 18th century, used to be produced from the ashes of plants. Known since antiquity, it was in 1807 that Humphry Davy put an end to the decades-long controversy about its nature as a compound. The technology behind potash production was implemented in Brazil by the Portuguese naturalist Frei Velloso. The…

As a model study for improving undergraduate organic chemistry laboratories with contemporary research concepts and practices, we evaluated a project module aiming at the synthesis of two porphyrin compounds. The module was implemented in a format that differed in several ways from that of a traditional course. It was designed for small student…

The topic of chemistry safety was included at the margins of traditional chemistry education in China. In order to understand the concerns of the safety issues based on the new chemistry curriculum in the mainland China secondary school, this study analyzed old and new secondary chemistry curriculum standards via the Natural Language Processing…

Across traditional lab-based science subjects, including biological sciences, most learning is discipline-specific and focused on developing scientific skills and knowledge. However, graduate employers are increasingly demanding that employees have additional skills, including the ability to recognise their own strengths and limitations, a skill…

Comprehensive curricula are described for middle and high school classrooms built around the synthesis of biodegradable calcium alginate capsules prepared from food-safe chemicals. Experiments and activities question whether calcium alginate capsules are a viable alternative to single-use water bottles and consider what characteristics are…

Recently, there have been many calls for an increase in instruction on the nature of science (NOS) in schools (i.e. NRC, 1996; NGSS Lead States, 2013). These calls recognize the importance of this topic at all levels of science education, but there is little guidance in terms of how to address it effectively in curricula. Similarly, there have…

A method for using electronic structure calculations to predict the standard molar enthalpy of combustion for hydrocarbons is presented. In this approach, simple geometry optimizations can be used to accurately compute the enthalpy of combustion within 3% of the experimental value using Hartree-Fock, MP2, or virtually any functional in density…

There is an increasing need for research chemists and biochemists to have a basic familiarity with computer programming. Adding programming content to already crowded STEM undergraduate curricula, however, can be challenging. When programming content is introduced within the chemistry curriculum, it is most often incorporated into upper division…

Providing opportunities for science, technology, engineering, and mathematics undergraduates to engage in authentic scientific practices is likely to influence their view of science and may impact their decision to persist through graduation. Laboratory courses provide a natural place to introduce students to scientific practices, but existing…

This study investigates the challenge faced by eighth-grade students at Southern State Middle School in grasping abstract concepts within the domains of physical science, physics, and chemistry. This difficulty is manifested in their poor performance on summative assessments. A comprehensive analysis of state-provided data, in conjunction with…