The central dogma of molecular biology describes the transfer of genetic information from nucleic acids to proteins and stipulates that the system cannot work in the reverse direction. As a fundamental principle in biology, the dogma is as influential as it is controversial. Some commentators have debated the central dogma's empirical accuracy…

Transcription is the critical first step in expressing a gene, during which an RNA polymerase (RNAP) synthesizes an RNA copy of one strand of the DNA that encodes a gene. Here we describe a laboratory experiment that uses a single assay to probe two important steps in transcription: (1) RNAP binding to DNA, and (2) the transcriptional activity of…

Graduates in biology or genetics learn Mendel's laws and Hardy-Weinberg equilibrium as students, and they know, use, and sometimes teach these concepts. However, it is unusual to learn about stochastic processes during the graduate studies of these topics, although the applications of Markov chains in the fields of genetics or biology are…

Issues associated with nature of science (NOS) have long been recognized as an essential component of scientific literacy. While consensus exists regarding the importance of an explicit reflective approach, precisely how to teach NOS remains elusive. The present study explores one particularly promising approach, namely the use of historical…

Integrating the nature of science (NOS) into textbooks is one of the challenges in science curricula. This case study assessed the issue based on a sample of high school biology textbooks in Mainland China. We quantitatively compared changes in the extent, quality, and distribution of NOS representations between 2004 and 2019 editions. Three main…

This study aimed to investigate research trends related to socio-scientific issues (SSI). The SSI articles analysed were from highest-rating five science education journals with the highest impact ratings, published between 2011 and 2022, including "Science Education" [SE], "Journal of Research in Science Teaching" [JRST],…

This study aims to categorize the scenarios designed on socio-scientific issues (SSIs) by prospective teachers who participated in an SSI-based instructional practice and to analyze these scenarios in terms of representing the nature of science (NOS) components. Sample of the study comprised SSI scenarios written by 30 third-year prospective…

In this article, we present how educational resources for zoology designed by undergraduate students help to propose means of action for teaching diversity and animal evolution in basic education. We realised that activities of creation and analysis of educational resources, in the context of didactic planning, have the potential to approximate…

The discovery of and research into penicillin resistance by Sir Edward Abraham and Sir Ernst Chain can be used to teach the concept of natural selection and also multiple nature of science (NOS) objectives associated with Next Generation Science Standards, such as "scientific knowledge is based on empirical evidence" and "science is…

Both accurate monitoring and adequate control are crucial for effective self-regulation when learning from problem-solving tasks. Prior research has shown that self-regulated learning is especially harmful for low prior knowledge students, given their difficulties with accurate monitoring and control decisions. Although many studies have indicated…

Dealing with multiple external representations (MERs) in science education is the key to students' understanding of science communication and becoming scientifically literate. It is generally accepted that learning scientific concepts, processes, and principles requires understanding and interacting with MERs. Science can be understood as a…

In the context of what are often highly compartmentalised curriculum requirements, this article considers the cyclical nature of the acquisition and transfer of knowledge in the education system in relation to those questions that transcend individual subjects as set out in traditional curriculum divisions. It also considers the detrimental…

In this manuscript, three science educators describe strategies used to effectively communicate about religiously and culturally sensitive science content and share lessons learned from their experiences. Mark A. Bloom (2019-2021 Fellow) describes the challenges he overcame in teaching climate change science at an evangelical university by…

"Sickle cell anemia: tracking down a mutation" is a full-day, inquiry-based, biology experience for high school students enrolled in genetics or advanced biology courses. In the experience, students use restriction endonuclease digestion, cellulose acetate gel electrophoresis, and microscopy to discover which of three putative patients…

The primary focus of this article is to illustrate how teachers can use contemporary socio-scientific issues to teach students about nature of scientific knowledge as well as address the science subject matter embedded in the issues. The article provides an initial discussion about the various aspects of nature of scientific knowledge that are…