Keto-enol tautomerization is paramount to understanding the mechanisms involved in many organic reactions and biochemical transformations. Isomerization of an enol to a carbonyl compound is typically introduced during the discussion of the acid-catalyzed electrophilic addition of water to alkynes. The tautomerization of carbonyl compounds to enol…

Ion transport, involving the diffusion and migration of ions within the electrolyte, stands as a fundamental concept in electrochemistry and serves as the driving force for electrochemical reactions. Electric double layers are critical in the fields of electrochemical energy storage and chemical conversion, constituting a central focus of…

Synthesis of (Z)-alkenes is challenging because the (E) stereoisomers are usually more stable. Energy transfer photocatalysis has emerged as an efficient strategy for (E) [right arrow] (Z) alkene isomerization. We report the development of an advanced undergraduate laboratory experiment that introduces students to contemporary organic…

This short paper presents an educational approach to teaching three popular methods for encoding DNA sequences: one-hot encoding, binary encoding, and integer encoding. Aimed at bioinformatics and computational biology students, our learning intervention focuses on developing practical skills in implementing these essential techniques for…

The role of computation in science is ever-expanding and is enabling scientists to investigate complex phenomena in more powerful ways and tackle previously intractable problems. The growing role of computation has prompted calls to integrate computational thinking (CT) into science instruction in order to more authentically mirror contemporary…

Computational models are employed to study and respond to pressing environmental issues such as groundwater contamination. This use of computational models, which often involves algorithms and uncertainty that are hidden to the public, has implications for environmental science literacy. This study applies a design-based research approach to…

To make sense of our interconnected and algorithm driven world, students increasingly need proficiency with computational thinking (CT), systems thinking (ST), and computational modeling. One aspect of computational modeling that can support students with CT, ST, and modeling is testing and debugging. Testing and debugging enables students to…

Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

Calculating analytical uncertainties as a part of method validation is a relevant aspect of field and laboratory practices in instrumental analytical chemistry subjects, which usually require complex algorithms. This work describes the development and didactic use of an automatic and straightforward informatics tool, implemented in an Excel macro,…

Knowledge-producing practices in sciences and engineering increasingly use computational means for modeling and working with data. Despite consensus regarding the importance of computational thinking in science and engineering, scholars differ in conceptualization of the primary purposes and role of its integration in K-12 science (Kafai &…

Background: Science teachers' understanding of the roles of computing practices in science frame how they enact scientific computational practices in their teaching and how their students perceive the relationship between computational practices and scientific endeavours. Objectives: This critical, integrative review synthesizes teacher learning…

Much research attention has been focused on learning through game playing. However, very little has been focused on student learning through game making, especially in science. Moreover, none of the studies on learning through making games has presented an account of how students engage in the process of game design in real time. The present study…

Increasing access to computational ideas and practices is one important reason to integrate computational thinking (CT) in science classrooms. While integrating CT into science classrooms broadens exposure to computing, it may not be enough to ensure equitable participation in the science classroom. Equitable participation is crucial because…

Circulatory system is a challenging subject for middle school students to learn and understand conceptual relationships. To address these challenges, this study developed plugged (computational thinking activities using computer) and unplugged (computational thinking activities without using computer) teaching modules that integrated computational…

This study was grounded in the spatial computational thinking model developed by the "3D Weather" project funded by the NSF STEM+C program. The model reflects a discipline-based perspective towards computational thinking and captures the spatial nature of computational thinking in meteorology and the reliance of computational thinking on…