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Cleary, Leonard J.; Byrne, John H.; Antzoulatos, Evangelos G.; Wainwright, Marcy L. – Learning & Memory, 2006
Repetitive, unilateral stimulation of "Aplysia" induces long-term sensitization (LTS) of ipsilaterally elicited siphon-withdrawal responses. Whereas some morphological effects of training appear only on ipsilateral sensory neurons, others appear bilaterally. We tested the possibility that contralateral morphological modifications may have…
Descriptors: Stimulation, Long Term Memory, Science Experiments, Scientific Methodology
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Ma, Yun L.; Tsai, Ming C.; Hsu, Wei L.; Lee, Eminy H.Y. – Learning & Memory, 2006
Previous studies showed that the serum- and glucocorticoid-inducible kinase ("sgk") gene plays an important role in long-term memory formation. The present study further examined the role of SGK in long-term potentiation (LTP). The dominant-negative mutant of "sgk," SGKS422A, was used to inactivate SGK. Results revealed a time-dependent increase…
Descriptors: Long Term Memory, Brain, Neuropsychology, Inhibition
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Maldonado, Hector; Romano, Arturo; Merlo, Emiliano; Freudenthal, Ramiro – Learning & Memory, 2005
Several studies support that stored memories undergo a new period of consolidation after retrieval. It is not known whether this process, termed reconsolidation, requires the same transcriptional mechanisms involved in consolidation. Increasing evidence supports the participation of the transcription factor NF-[Kappa]B in memory. This was…
Descriptors: Molecular Biology, Recall (Psychology), Long Term Memory, Animals