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Concomitant Medication Use in Children with Autism Spectrum Disorder: Data from the Autism Biomarkers Consortium for Clinical Trials
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Shurtz, Logan; Schwartz, Chloe; DiStefano, Charlotte; McPartland, James C.; Levin, April R.; Dawson, Geraldine; Kleinhans, Natalia M.; Faja, Susan; Webb, Sara J.; Shic, Frederick; Naples, Adam J.; Seow, Helen; Bernier, Raphael A.; Chawarska, Katarzyna; Sugar, Catherine A.; Dziura, James; Senturk, Damla; Santhosh, Megha; Jeste, Shafali S. – Autism: The International Journal of Research and Practice, 2023
Children with autism spectrum disorder are prescribed various medications to address behavior and mood. In clinical trials, individuals taking concomitant psychotropic medications often are excluded to maintain homogeneity and prevent contamination of clinical endpoints. However, this choice may compromise the representativeness of the sample. In…
Descriptors: Autism Spectrum Disorders, Drug Therapy, Incidence, Child Behavior
Conducting Research with Minimally Verbal Participants with Autism Spectrum Disorder
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Tager-Flusberg, Helen; Plesa Skwerer, Daniela; Joseph, Robert M.; Brukilacchio, Brianna; Decker, Jessica; Eggleston, Brady; Meyer, Steven; Yoder, Anne – Autism: The International Journal of Research and Practice, 2017
A growing number of research groups are now including older minimally verbal individuals with autism spectrum disorder in their studies to encompass the full range of heterogeneity in the population. There are numerous barriers that prevent researchers from collecting high-quality data from these individuals, in part because of the challenging…
Descriptors: Autism, Pervasive Developmental Disorders, Verbal Communication, Communication Problems
Overcoming Hurdles to Intervention Studies with Autistic Children with Profound Communication Difficulties and Their Families
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McKinney, Ailbhe; Weisblatt, Emma J. L.; Hotson, Kathryn L.; Bilal Ahmed, Zahra; Dias, Claudia; BenShalom, Dorit; Foster, Juliet; Murphy, Suzanne; Villar, Sofía S.; Belmonte, Matthew K. – Autism: The International Journal of Research and Practice, 2021
Autistic children and adults who are non-verbal/minimally verbal or have an intellectual disability have often been excluded from Autism Spectrum Disorder research. Historical, practical and theoretical reasons for this exclusion continue to deter some researchers from work with this underserved population. We discuss why these reasons are neither…
Descriptors: Autism, Pervasive Developmental Disorders, Communication Disorders, Intervention