Cluster randomized trials (CRTs) are commonly used to evaluate the causal effects of educational interventions, where the entire clusters (e.g., schools) are randomly assigned to treatment or control conditions. This study introduces statistical methods for designing and analyzing two-level (e.g., students nested within schools) and three-level…

Background: Education scientists are increasingly interested in constructing interventions that are adaptive over time to suit the evolving needs of students, classrooms, or schools. Such "adaptive interventions" (also referred to as dynamic treatment regimens or dynamic instructional regimes) determine which treatment should be offered…

Comprehensive evaluation of treatment effects is aided by considerations for moderated effects. In educational research, the combination of natural hierarchical structures and prevalence of group-administered or shared facilitator treatments often produces three-level partially nested data structures. Literature details planning strategies for a…

Optimal sampling frameworks attempt to identify the most efficient sampling plans to achieve an adequate statistical power. Although such calculations are theoretical in nature, they are critical to the judicious and wise use of funding because they serve as important starting points that guide practical discussions around sampling tradeoffs and…

Traditionally, cluster randomized controlled trials are analyzed with the average intervention effect of interest. However, in populations that contain higher degrees of heterogeneity or variation may differ across different values of a covariate, which may not be optimal. Within education and social science contexts, exploring the variation in…

Cluster randomized control trials often incorporate a longitudinal component where, for example, students are followed over time and student outcomes are measured repeatedly. Besides examining how intervention effects induce changes in outcomes, researchers are sometimes also interested in exploring whether intervention effects on outcomes are…

Cluster randomized trials (CRTs) are commonly used to evaluate educational interventions, particularly their effectiveness. Recently there has been greater emphasis on using these trials to explore cost-effectiveness. However, methods for establishing the power of cluster randomized cost-effectiveness trials (CRCETs) are limited. This study…

Sample size determination in multilevel randomized trials (MRTs) and multilevel regression discontinuity designs (MRDDs) can be complicated due to multilevel structure, monetary restrictions, differing marginal costs per treatment and control units, and range restrictions in sample size at one or more levels. These issues have sparked a set of…

When well-implemented, mediation analyses play a critical role in probing theories of action because their results help lay the ground work for the critical development of a treatment and the iterative advancement of theories that are foundational to a discipline. Despite strong interest in designs that incorporate mediation, few studies have…

Conventional optimal design frameworks consider a narrow range of sampling cost structures that thereby constrict their capacity to identify the most powerful and efficient designs. We relax several constraints of previous optimal design frameworks by allowing for variable sampling costs in cluster-randomized trials. The proposed framework…

In randomized control trials (RCT), the recent focus has shifted to how an intervention yields positive results on its intended outcome. This aligns with the recent push of implementation science in healthcare (Bauer et al., 2015) but goes beyond this. RCTs have moved to evaluating the theoretical framing of the intervention as well as differing…

Professional development for teachers is regarded as one of the principal pathways through which we can understand and cultivate effective teaching and improve student outcomes. A critical component of studies that seek to improve teaching through professional development is the detailed assessment of the intermediate teacher development processes…

Cluster Randomized Trial (CRT) designs are inherently multilevel and reflect the hierarchical structure of schools and the wider education system. To capture this multilevel nature, CRTs are commonly analysed using multilevel (or hierarchical) linear models. It is fairly common for CRT designs and analyses to include school and individual/pupil…

Researchers are often interested in whether the effects of an intervention differ conditional on individual- or group-moderator variables such as children's characteristics (e.g., gender), teacher's background (e.g., years of teaching), and school's characteristics (e.g., urbanity); that is, the researchers seek to examine for whom and under what…

Recent studies show cluster randomized trials may be well powered to detect mediation or indirect effects in multilevel settings. However, literature has rarely provided guidance on designing cluster-randomized trials aim to assess indirect effects. In this study, we developed closed-form expression to estimate the variance of and the statistical…