The purpose of this dissertation is to develop principles and strategies for and identify limitations of multisite cluster randomized trials in the context of partially and fully nested designs. In the first study, I develop principles of estimation, sampling variability, and inference for studies that leverage multisite designs within the context…

This study introduces a novel approach for conducting Systematic Literature Reviews(SLRs) by incorporating a unique mixed-methods design into the well-established SLR process. The proposed approach, identified as Mixed-Methods Based Systematic Literature Review (MMB-SLR), not only provides researchers with a broader perspective on their research…

In randomized control trials (RCT), the recent focus has shifted to how an intervention yields positive results on its intended outcome. This aligns with the recent push of implementation science in healthcare (Bauer et al., 2015) but goes beyond this. RCTs have moved to evaluating the theoretical framing of the intervention as well as differing…

Multilevel experiments have been widely used in education and social sciences to evaluate causal effects of interventions. Two key considerations in designing experimental studies are statistical power and the minimal use of resources. Optimal design framework simultaneously addresses both considerations. This dissertation extends previous optimal…