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Qi, Hongchao; Rizopoulos, Dimitris; Rosmalen, Joost – Research Synthesis Methods, 2023
The meta-analytic-predictive (MAP) approach is a Bayesian method to incorporate historical controls in new trials that aims to increase the statistical power and reduce the required sample size. Here we investigate how to calculate the sample size of the new trial when historical data is available, and the MAP approach is used in the analysis. In…
Descriptors: Sample Size, Computation, Meta Analysis, Bayesian Statistics
Gagnon-Bartsch, J. A.; Sales, A. C.; Wu, E.; Botelho, A. F.; Erickson, J. A.; Miratrix, L. W.; Heffernan, N. T. – Grantee Submission, 2019
Randomized controlled trials (RCTs) admit unconfounded design-based inference--randomization largely justifies the assumptions underlying statistical effect estimates--but often have limited sample sizes. However, researchers may have access to big observational data on covariates and outcomes from RCT non-participants. For example, data from A/B…
Descriptors: Randomized Controlled Trials, Educational Research, Prediction, Algorithms