Many neurological and psychiatric disorders are characterized by deficits in cognitive flexibility. Modeling cognitive flexibility in mice enables the investigation of mechanisms underlying these deficits. The majority of currently available behavioral tests targeting this cognitive domain are reversal learning tasks that require scheduled food…

A functional analysis identified the reinforcer maintaining feces throwing and spitting exhibited by a captive adult chimpanzee ("Pan troglodytes"). The implementation of a function-based treatment combining extinction with differential reinforcement of an alternate behavior decreased levels of inappropriate behavior. These findings further…

The goal of this series of experiments was to develop an operant choice procedure to examine rapidly the punishing effects of intravenous drugs in rats. First, the cardiovascular effects of experimenter-administered intravenous histamine, a known aversive drug, were assessed to determine a biologically active dose range. Next, rats responded on…

In a previous issue of "The Behavior Analyst," the authors discussed the ambiguities that surround the distinction between positive and negative reinforcement. Seven distinguished behavior analysts commented on their article. The authors believe that this dialogue represented a constructive step toward clarification of an important concept within…

Rats obtained food-pellet reinforcers by nose poking a lighted key. Experiment 1 examined resistance to extinction following single-schedule training with different variable-interval schedules, ranging from a mean interval of 16 min to 0.25 min. That is, for each schedule, the rats received 20 consecutive daily baseline sessions and then a session…