Background: Few studies have investigated functional and behavioural variables of Cornelia de Lange Syndrome (CdLS) in a large sample of individuals. The aim of this study is to provide greater insight into the clinical, behavioural and cognitive characteristics that are associated with CdLS. Methods: In total, 56 individuals with CdLS…

As part of the Combating Autism Act of 2006, the members of the Interagency Autism Coordinating Committee (IACC) are required to develop an annual "Summary of Advances" to describe each year's top advances in autism spectrum disorder (ASD) research. These advances represent significant progress in the early diagnosis of ASD, understanding the…

Autism presents parents and families with many challenges under normal circumstances. Autism in a military family magnifies many of those challenges and adds a few more that are unique to the demands of military life and service, further complicating an already complex neurobiological disorder. Military sources indicate that more than 13,000…

A study of 20 children (ages 3-6) with autism and 20 children with pervasive developmental disorders (PDD) examined the validity of a Dutch version of the revised Psychoeducational Profile (PEP-R). No differences were found on the PEP-R developmental subscales, but on the pathology subscales children with autism showed more severe behavior than…

A study compared characteristics of individuals with mild retardation and clinically classified as autistic disorder (n=205), Pervasive Developmental Disorder Not Otherwise Specified (PDDNOS) (n=80), and other non-PDD disorders (n=174). Only a few items from the ICD-10 and DSM-IV discriminated the PDDNOS group from other disorders. Suggested…

An evaluation was made of the empirical validity of the Diagnostic Assessment for the Severely Handicapped-II (DASH-II) with 51 individuals with severe/profound mental retardation, some of whom were also diagnosed with autism, and controls. The Autism/Pervasive Developmental Disorder subscale of the DASH-II was internally consistent and just as…

Describes the development of the Children's Social Behavior Questionnaire (CSBQ), an instrument designed to provide an extensive list of behaviors frequently observed in children with Pervasive Developmental Disorder Not Otherwise Specified. The successful results of the CSBQ in distinguishing the characteristics of this disability are reported.…

Rich with clinical insights, this volume reviews the state of the science of identifying and treating autism spectrum disorders (ASD) in very young children. Leading authorities examine critical research issues and present innovative approaches to assessing social, cognitive, adaptive, communication, and sensory-motor impairments in the first two…

Asserts that although no instrument has proved sufficiently robust to recommend universal screening, screening instruments for autism spectrum disorder (ASD) can play an important role. Discusses the clinical issues raised in screening for a developmental disorder, including risk status, management advice, and availability of services. Asserts…

In this article, the author shares some insights on the characteristics of a person with Asperger's syndrome, a condition on the higher-functioning end of autism spectrum disorders (ASD). Born in 1955, the author was raised in rural South Auckland. As a baby, she propelled herself around the floor on her stomach, using her limbs as flippers,…

The Scale of Pervasive Developmental Disorder in Mentally Retarded Persons (PDD-MRS) is described. The PDD-MRS is a simple classification and screening instrument devised for identification of autistic disorders (of the entire spectrum) in persons with mental retardation from mild to profound levels, age-range 2-55 years. The norms of the scale…

This article reviews epidemiological studies of autism and related disorders. Study designs and sample characteristics are summarized. Currently, conservative prevalence estimates are: 13/10000 for autistic disorder, 21/10000 for pervasive developmental disorders not otherwise specified, 2.6/10000 for Asperger disorder, and 2/100000 for childhood…

Teachers and parents completed the Autism Behavior Checklist (ABC) for 17 congenitally blind children (ages 4 to 11). The modified format ABC completed by teachers detected three of four children with pervasive developmental disorder without any false positives. (Author/SW)

A study involving 18 individuals with pervasive developmental disorders (PDD) (ages 9-21) and 67 controls found total score on the Biber Cognitive Estimation Test for both individuals with PDD and controls progressed consistently with mental age, development being the most dramatic around the mental age of 8 years. (Contains references.)…

Investigates validity of the Autism Behavior Checklist (ABC) measuring characteristics of individuals with autism, and the Pervasive Developmental Disorder Rating Scale (PDDRS) measuring pervasive developmental disorders. Results showed both instruments significantly discriminated between participants with autistic disorder and children with…