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Direct linkDaniel A. Geller; Mia Grossman – Journal of Attention Disorders, 2024
Objective: To use a family genetic study to evaluate familial risk of obsessive compulsive disorder (OCD) and common comorbid illnesses in first-degree relatives of pediatric-onset probands with primary OCD. Method: One hundred and thirty youth with OCD and their 133 siblings and 241 parents and 49 pediatric controls were directly evaluated along…
Descriptors: Heredity, Anxiety Disorders, Comorbidity, Child Health
Márquez-Caraveo, María Elena; Ibarra-González, Isabel; Rodríguez-Valentín, Rocío; Ramírez-García, Miguel Ángel; Pérez-Barrón, Verónica; Lazcano-Ponce, Eduardo; Vela-Amieva, Marcela – Journal of Autism and Developmental Disorders, 2021
The objective of our study was to evaluate the frequency of treatable inborn errors of metabolism (IEM) in a clinical sample of Mexican children and adolescents with neurodevelopmental disorders (NDD). Amino acids and acylcarnitines in blood samples of 51 unrelated children and adolescents were analyzed by tandem mass spectrometry to detect…
Descriptors: Foreign Countries, Mexicans, Clinical Diagnosis, Genetic Disorders
Merker, Sören; Reif, Andreas; Ziegler, Georg C.; Weber, Heike; Mayer, Ute; Ehlis, Ann-Christine; Conzelmann, Annette; Johansson, Stefan; Müller-Reible, Clemens; Nanda, Indrajit; Haaf, Thomas; Ullmann, Reinhard; Romanos, Marcel; Fallgatter, Andreas J.; Pauli, Paul; Strekalova, Tatyana; Jansch, Charline; Vasquez, Alejandro Arias; Haavik, Jan; Ribasés, Marta; Ramos-Quiroga, Josep Antoni; Buitelaar, Jan K.; Franke, Barbara; Lesch, Klaus-Peter – Journal of Child Psychology and Psychiatry, 2017
Background: Attention-deficit/hyperactivity disorder (ADHD) is a common, highly heritable neurodevelopmental disorder with profound cognitive, behavioral, and psychosocial impairments with persistence across the life cycle. Our initial genome-wide screening approach for copy number variants (CNVs) in ADHD implicated a duplication of…
Descriptors: Attention Deficit Hyperactivity Disorder, Neurological Impairments, Genetic Disorders, Physiology
Suter, Bernhard; Treadwell-Deering, Diane; Zoghbi, Huda Y.; Glaze, Daniel G.; Neul, Jeffrey L. – Journal of Autism and Developmental Disorders, 2014
Mutations in "Methyl-CpG-Binding protein 2" ("MECP2") are commonly associated with the neurodevelopmental disorder Rett syndrome (RTT). However, some people with RTT do not have mutations in "MECP2," and interestingly there have been people identified with "MECP2" mutations that do not have the clinical…
Descriptors: Genetics, Genetic Disorders, Neurological Impairments, Patients
Reeb-Sutherland, Bethany C.; Fox, Nathan A. – Journal of Autism and Developmental Disorders, 2015
Eyeblink conditioning (EBC) is a classical conditioning paradigm typically used to study the underlying neural processes of learning and memory. EBC has a well-defined neural circuitry, is non-invasive, and can be employed in human infants shortly after birth making it an ideal tool to use in both developing and special populations. In addition,…
Descriptors: Eye Movements, Neurological Impairments, Autism, Pervasive Developmental Disorders
Grant, Patrick A.; Grant, Nia A. – Advances in Special Education, 2015
The treatment and care of persons with a disability should and must be all encompassing. With the expansion of the knowledge that proper dieting can make a difference in the individual's development and quality of life, attention must be focused on using proper food intake to remediate the negative impact of a disability. Food is related to proper…
Descriptors: Dietetics, Allied Health Personnel, Special Needs Students, Students with Disabilities
Huang, Jia; Yang, Bin-rang; Zou, Xiao-bing; Jing, Jin; Pen, Gang; McAlonan, Grainne M.; Chan, Raymond C. K. – Research in Developmental Disabilities: A Multidisciplinary Journal, 2012
The current study aimed to investigate temporal processing in Chinese children with Attention-Deficit-Hyperactivity Disorder(ADHD) using time production, time reproduction paradigm and duration discrimination tasks. A battery of tests specifically designed to measure temporal processing was administered to 94 children with ADHD and 100…
Descriptors: Attention Deficit Hyperactivity Disorder, Multivariate Analysis, Genealogy, Cognitive Ability
Templer, Alexandra K.; Titus, Jeffrey B.; Gutmann, David H. – Journal of Attention Disorders, 2013
Cognitive problems are common in children with neurofibromatosis type 1 and they can often complicate treatment. The current literature review examines cognitive functioning in neurofibromatosis type 1, with a specific focus on executive functioning. This includes exploration of how deficits in executive functioning are expressed in children with…
Descriptors: Genetic Disorders, Neurological Impairments, Cognitive Ability, Cognitive Processes
Tye, Charlotte; Rijsdijk, Fruhling; Greven, Corina U.; Kuntsi, Jonna; Asherson, Philip; McLoughlin, Grainne – Journal of Child Psychology and Psychiatry, 2012
Background: Attention deficit hyperactivity disorder (ADHD) is a common and highly heritable neurodevelopmental disorder with a complex aetiology. The identification of candidate intermediate phenotypes that are both heritable and genetically linked to ADHD may facilitate the detection of susceptibility genes and elucidate aetiological pathways.…
Descriptors: Attention Deficit Hyperactivity Disorder, Twins, Genetics, Genetic Disorders
Erdodi, Laszlo; Lajiness-O'Neill, Renee; Schmitt, Thomas A. – Journal of Autism and Developmental Disorders, 2013
Visual and auditory verbal learning using a selective reminding format was studied in a mixed clinical sample of children with autism spectrum disorder (ASD) (n = 42), attention-deficit hyperactivity disorder (n = 83), velocardiofacial syndrome (n = 17) and neurotypicals (n = 38) using the Test of Memory and Learning to (1) more thoroughly…
Descriptors: Attention Deficit Hyperactivity Disorder, Verbal Learning, Autism, Visual Learning
Mathews, Carol A.; Grados, Marco A. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: Tourette syndrome (TS) is a neuropsychiatric disorder with a genetic component that is highly comorbid with obsessive-compulsive disorder (OCD) and attention deficit/hyperactivity disorder (ADHD). However, the genetic relations between these disorders have not been clearly elucidated. This study examined the familial relations among TS,…
Descriptors: Attention Deficit Hyperactivity Disorder, Anxiety Disorders, Genetics, Neurological Impairments
Pozzi-Monzo, Maria – Journal of Child Psychotherapy, 2012
This paper explores further the vast topic of child neuropsychiatric disorders--ADHD in particular. It refers to and expands on issues debated in an earlier paper "Ritalin for whom?". In that paper, it was argued that those who benefitted most from children taking Ritalin were parents and teachers struggling with uncontained and out-of-control…
Descriptors: Genetics, Vignettes, Attention Deficit Hyperactivity Disorder, Psychotherapy
Ben-Pazi, Hilla; Jaworowski, Solomon; Shalev, Ruth S – Developmental Medicine & Child Neurology, 2011
Aim: The cognitive and psychiatric aspects of adult movement disorders are well established, but specific behavioural profiles for paediatric movement disorders have not been delineated. Knowledge of non-motor phenotypes may guide treatment and determine which symptoms are suggestive of a specific movement disorder and which indicate medication…
Descriptors: Anxiety Disorders, Diseases, Attention Deficit Hyperactivity Disorder, Depression (Psychology)
Gadow, Kenneth D.; Roohi, Jasmin; Devincent, Carla J.; Kirsch, Sarah; Hatchwell, Eli – Journal of Autism and Developmental Disorders, 2009
The aim of the study is to examine rs4680 ("COMT") and rs6265 ("BDNF") as genetic markers of anxiety, ADHD, and tics. Parents and teachers completed a DSM-IV-referenced rating scale for a total sample of 67 children with autism spectrum disorder (ASD). Both "COMT" (p = 0.06) and "BDNF" (p = 0.07) genotypes were marginally significant for teacher…
Descriptors: Autism, Rating Scales, Anxiety, Genetics
Niklasson, Lena; Gillberg, Christopher – Research in Developmental Disabilities: A Multidisciplinary Journal, 2010
The primary objective of this study was to study the impact of ASD/ADHD on general intellectual ability and profile, executive functions and visuo-motor skills in children and adults with 22q11 deletion syndrome (22q11DS). A secondary aim was to study if gender, age, heart disease, ASD, ADHD or ASD in combination with ADHD had an impact on general…
Descriptors: Heart Disorders, Intelligence Quotient, Neuropsychology, Etiology
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