Computing the mean and covariance matrix of some multivariate distributions, in particular, multivariate normal distribution and Wishart distribution are considered in this article. It involves a matrix transformation of the normal random vector into a random vector whose components are independent normal random variables, and then integrating…

Both doubly multivariate and multivariate mixed models of analyzing repeated measures on multivariate responses are reviewed. Given multivariate normality, a condition called multivariate sphericity of the covariance matrix is both necessary and sufficient for the validity of the multivariate mixed model analysis. (SLD)