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Kontopantelis, Evangelos – Research Synthesis Methods, 2018
Background: Individual patient data (IPD) meta-analysis allows for the exploration of heterogeneity and can identify subgroups that most benefit from an intervention (or exposure), much more successfully than meta-analysis of aggregate data. One-stage or two-stage IPD meta-analysis is possible, with the former using mixed-effects regression models…
Descriptors: Patients, Medical Research, Meta Analysis, Intervention