Patient education about managing chronic illness is critical given the growing burden of health care costs on society. Transplant recipients are forced into obtaining and learning how to understand complex information. The purpose of this mixed methods study was to highlight learning barriers and effective techniques used to manage care through the lived experiences of 30 randomly selected transplant recipients. The study design was informed by National Center for Education Statistics data highlighting learning activities used by the general population of adult learners. Participants were asked through an online survey tool which learning activities were most effective during rehabilitation and was/were the source(s) of critical information. Their experiences of achieving post organ transplant success were classified into 6 categories: physical activity, gratitude, education, personal accountability, confidence/empowerment, and the significance of life. The results confirmed presence of adult learning assumptions found in Knowles's theory of andragogy and leadership attributes among the study participants. A process map similar to those used in Lean Six Sigma was constructed to highlight the optimum process flow for learning how to best manage post transplant care. From the map, a Pareto chart using descriptive statistics was also created to show the barriers encountered during the learning process. Given the rising number of patients on transplant waiting lists, societal costs, and its effects on recipients, this study is expected to contribute to positive social change by providing educators, care givers, and patients alike critical information about the preferred learning activities and the barriers to overcome for a more effective post transplant rehabilitation process. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com.bibliotheek.ehb.be/en-US/products/dissertations/individuals.shtml.]