The principles of modern genetics are extended to study the extinction probabilities of such genetic diseases as sickle-cell anemia, Tay-Sachs disease, and cystic fibrosis. (JT)

The problems involved in making reservations for airline flights is discussed in creating a mathematical model designed to maximize an airline's income. One issue not considered in the model is any public relations problem the airline may have. The model does take into account the issue of denied boarding compensation. (MP)