Behavioral studies indicate deficits in phonological working memory (WM) and executive functioning in dyslexics. However, little is known about the underlying functional neuroanatomy. In the present study, neural correlates of WM in adolescents and young adults with dyslexia were investigated using event-related functional magnetic resonance…

Recent data suggest recovery of language systems but persistent structural abnormalities in the prematurely born. We tested the hypothesis that subjects who were born prematurely develop alternative networks for processing language. Subjects who were born prematurely (n = 22; 600-1250 g birth weight), without neonatal brain injury on neonatal…

Speech-associated gestures are hand and arm movements that not only convey semantic information to listeners but are themselves actions. Broca's area has been assumed to play an important role both in semantic retrieval or selection (as part of a language comprehension system) and in action recognition (as part of a "mirror" or…

This study looks at whether conventional and anomalous metaphors are processed in different locations in the brain while being read when compared with a literal condition in Mandarin Chinese. We find that conventional metaphors differ from the literal condition with a slight amount of increased activation in the right inferior temporal gyrus. In…

We present two bilingual patients without language disorders in whom involuntary language switching was induced. The first patient switched from Dutch to English during a left-sided amobarbital (Wada) test. Functional magnetic resonance imaging yielded a predominantly left-sided language distribution similar for both languages. The second patient…

In this paper we attempt to relate the prelexical processing of speech, with particular emphasis on functional neuroimaging studies, to the study of auditory perceptual systems by disciplines in the speech and hearing sciences. The elaboration of the sound-to-meaning pathways in the human brain enables their integration into models of the human…

The cortical regions of the brain traditionally associated with the comprehension of language are Wernicke's area and Broca's area. However, recent evidence suggests that other brain regions might also be involved in this complex process. This paper describes the opportunity to evaluate a large number of brain-injured patients to determine which…

It has been commonly agreed that developmental dyslexia in different languages has a common biological origin: a dysfunction of left posterior temporal brain regions dealing with phonological processes. Siok, Perfetti, Jin, and Tan (2004, "Nature," 431, 71-76) challenge this biological unity theory of dyslexia: Chinese dyslexics show no deficits…

Although there is a strong link between the right hemisphere and understanding emotional prosody in speech, there are few data on how the right hemisphere is implicated for understanding the emotive "attitudes" of a speaker from prosody. This report describes two experiments which compared how listeners with and without focal right hemisphere…

It is widely accepted that the cerebellar and basal ganglia control circuits contribute to the programming of movement. Converging evidence from neuroimaging, limb control, and neuropsychological studies suggests that (1) people with cerebellar disease have reduced ability to program movement sequences in advance of movement onset and (2) people…

Infants younger than 20 months of age interpret both words and symbolic gestures as object names. Later in development words and gestures take on divergent communicative functions. Here, we examined patterns of brain activity to words and gestures in typically developing infants at 18 and 26 months of age. Event-related potentials (ERPs) were…

Purpose: To examine the behavioral effects and neural activation patterns associated with implicit semantic processing influences on phonological judgments during reading in children and adults. Method: Whole-head magnetoencephalography (MEG) recordings were obtained from 2 groups, children (9-13 years) and adults, performing a homophone judgment…

There is debate as to the relationship between mathematical ability and language. Some research has suggested that common processes underlie arithmetic and grammar while other research has suggested that these are distinct processes. The current study aimed to address this issue in a large group of 68 left hemisphere stroke patients who were all…

The structure of the brain and the nature of evolution suggest that, despite its uniqueness, language likely depends on brain systems that also subserve other functions. The declarative/procedural (DP) model claims that the mental lexicon of memorized word-specific knowledge depends on the largely temporal-lobe substrates of declarative memory,…

Broca's region in the dominant cerebral hemisphere is known to mediate the production of language but also contributes to comprehension. This region evolved only in humans and is constituted of Brodmann's areas 44 and 45 in the inferior frontal gyrus. There is, however, evidence that Broca's region overlaps, at least in part, with the ventral…