We created a novel laboratory experience where undergraduate students explore the techniques used to study protein misfolding, unfolding, and aggregation. Despite the importance of protein misfolding and aggregation diseases, protein unfolding is not typically explored in undergraduate biochemistry laboratory classes. Yeast alcohol dehydrogenase…

Understanding potentiometry is a difficult task when students in initial courses of Analytical Chemistry are first introduced to instrumental techniques. The closest instrument to them is a pH meter, which is frequently used as a "black box", without a real understanding of how it works. Here we present the assembly of jelly modules that…

During the coronavirus pandemic, there have been significant challenges in the remote teaching and demonstration of experiments, especially those that require laboratory testing equipment. With a desire to give students a feel for our materials laboratory on open days and allow them to gain a deeper understanding of what materials science and…

An experiment exploring the chemistry of the carbonyl group for the one-step synthesis of "trans"-4,5- dibenzylaminocyclopent-2-enone is described. The reaction of furfural and dibenzylamine in the environmentally friendly solvent ethanol and catalyzed by the Lewis acid ErCl[subscript 3]·6H[subscript 2]O afforded the product in high…

Because she had been blind since birth, we knew that our new student, Cricket, would be unable to make the necessary measurements needed to get any meaningful lab data while all of the other students would be able to use highly accurate commercial Vernier calipers. All we had on loan for Cricket was a Brailled plastic tactile meter stick with low…

Light irradiance measurements are important for students grappling with abstract optical phenomena such as the inverse square law, polarization, diffraction, interference, and spectroscopy. A variety of commercial light sensors are available from scientific vendors such as the CI-6504A from PASCO scientific and the LS-BTA from Vernier Software and…

The FluAnisot educational software package is a fully contained tutorial on the technique of fluorescence anisotropy measurement as well as a simulator on which two experiments can be performed. The procedure for each of the experiments is also contained within the package along with example analyses of results that were obtained using the…

The speed of sound is a physical property that can be measured easily in the lab. However, finding an inexpensive and intuitive way for students to determine this speed has been more involved. The introduction of affordable consumer-grade high-speed cameras (such as the Exilim EX-FC100) makes conceptually simple experiments feasible. Since the…

Described is a conductiometric method for following the course of diffusion of aquated ions through a cellulose membrane. Several experiments using the method are described. (Author/SA)

Describes the infrared analysis of geological specimens which can form the basis of a laboratory exercise, allowing some minerals to be identified by "fingerprint" technique. Students can gain insight into the concept of symmetry and environment around an atom. (Author/SA)

Describes an electronic technique for making a series of timing measurements in quick succession, using the signal from one photodiode. Two undergraduate experiments, one on linear momentum and the other on angular momentum conservation, are included. (HM)