In this guided-inquiry lesson, students were tasked with determining the efficacy of an at-home drinking water filter at removing lead (Pb) from tap water using graphite furnace atomic absorption spectroscopy by determining the concentration of lead before and after filtration. The lesson was structured to allow students to choose and perform…

A newly developed laboratory learning program for high school chemistry courses is discussed, in which students discover the chemical mechanism governing exothermic phenomena during the reaction between a heating agent, namely, calcium oxide (CaO)--aluminum (Al) mixture, and water. Based on prior knowledge of simple heating agents such as CaO, the…

A set of inexpensive and pedagogically rich experiments focusing on S[subscript N]1, E1, and E2 reactions have been updated to include modern computational and spectroscopic analyses. The S[subscript N]1 experiment involves treatment of "tert"-amyl alcohol with hydrochloric acid to generate the corresponding alkyl chloride, which is used…

A laboratory experiment that involves the synthesis, characterization, and application exploration of a metal-organic framework (MOF) has been developed for first-year undergraduates in the Faculty of Engineering at National University of Singapore. The desired MOF material was prepared from commercially available reagents in a facile…

Biodiesel is an important biomass, largely employed in the transport sector and produced from vegetable oils. Additionally, waste cooking oils may be reused to produce biodiesel fuel, minimizing environmental pollution. A laboratory experiment that affords a widespread way to discuss degradation concepts and tools for used vegetable oil…

When injecting dye into a vortex, one finds that the dye remains captured around the vortex core over minutes, despite the fact that the vortex (and the dyed region) is strongly time-dependent. According to a recent theory, three-dimensional time-dependent vortices should be defined as rotating, material-holding regions of the fluid. Vortices…

Carbohydrates are an essential group of molecules to the organic chemistry classroom providing molecular relevance to a common ingredient in chemical biology. While the meticulous elucidation of the carbohydrate structures by Fischer and others is an engaging topic in the lecture, there are few laboratory experiments that can emulate carbohydrate…

A continuous flow photopinacol coupling of benzophenone has been developed and implemented in the undergraduate laboratory. This photoreduction was accomplished using 2-propanol as an H atom donor and cosolvent in the reaction. The simple and inexpensive UV light source and flow reactor design (less than $350/photochemical flow system) provide an…

Williamson ether experiments are commonly performed by students in undergraduate organic chemistry instructional laboratory courses. In this multioutcome experiment, students were provided 4-bromophenol and one of three alkyl halides: 1-bromopentane, 1-bromobutane, or 1-bromo-3-methylbutane. The alkyl halides served as the unknown component of the…

An undergraduate organic chemistry experiment has been developed that features asymmetric synthesis of an enantioenriched secondary alcohol, followed by determination of its absolute configuration using the competing enantioselective conversion (CEC) method. Students are given a ketone and an unknown enantiomer of CBS (Corey-Bakshi-Shibata)…

Transcription is the critical first step in expressing a gene, during which an RNA polymerase (RNAP) synthesizes an RNA copy of one strand of the DNA that encodes a gene. Here we describe a laboratory experiment that uses a single assay to probe two important steps in transcription: (1) RNAP binding to DNA, and (2) the transcriptional activity of…

While elimination reactions are ubiquitous in organic chemistry textbooks, their implementation in undergraduate laboratories still suffers from a lack of reliable and easy setup procedures. This paper describes an easy-to-implement set of elimination experiments in the pentanol and bromopentane series using a modified Hickman distillation head.…

In this laboratory experiment, a guided inquiry exploring the physicochemical principles of the dissolution of Ca(OH)[subscript 2](s) in water is proposed for laboratory classes in university and high school. As part of students' inquiry, two experimental approaches are used. One is the change in solubility with temperature revealed by measuring…

The COVID-19 pandemic and its related restrictions forced the reorganization of learning methodology and gave a central role to remote learning. Laboratory experiments are the most affected activity, and several alternatives were described. This work proposes to create calculation tools by simply programming in Visual Basic of Excel to emulate the…

An approach to online laboratory exercises for analytical chemistry students with demonstrated practical exercises through the use of remote-controlled gas chromatography (GC) instrumentation is discussed. The approach allows for a practical-based learning activity to be carried out by students who are unable to attend in-person laboratory…