We present a modernization of the undergraduate physical chemistry laboratory experiment for determining the speed of sound in various gases from resonant frequencies in a spherical resonator. The resonator (schematic IR = 7.5 cm) is constructed by 3D printing with eco-friendly poly(lactic acid), a commercially viable alternative to traditional…

The knowledge of the mechanical properties of polymers and other materials is essential for several tasks in the field of materials science, like component design and material development. The tensile test is one method of determining many of the material's most defining mechanical characteristics. However, the teaching of laboratory experiments…

Interdisciplinary experiments within chemistry are very important for the improvements in the overall quality of the education received by students. In this work, we describe an interdisciplinary experiment that was successfully completed by undergraduate students. This training integrates multiple disciplines including natural product medicinal…

Polymer chemistry is an important subject in the undergraduate chemistry curriculum. It is required for ACS-certified degrees and significantly connects to real world issues like the plastic waste crisis. While some concepts of polymer chemistry can be incorporated into lecture courses, students' understanding of material properties and…

Three direct complexometric titration methods for bismuth subsalicylate determination in over-the-counter stomach relief caplets and liquids are presented, as well as a UV-vis assay, for use in student laboratories. The main difference between titration methods is the choice of indicator; either xylenol orange (XO), pyrocatechol violet (PV), or…

The Förster resonance energy transfer (FRET) melting assay intends to evaluate the unfolding, denaturation process of DNA secondary structures, and its stabilization using compounds known as DNA binders, some of which are highly specific for G-quadruplex DNAs versus duplex DNAs. First, students determined the melting temperature (T[subscript m])…

Here, we propose a laboratory exercise to quickly determine single nucleotide polymorphisms (SNPs) in human "alcohol dehydrogenase 1B (ADH1B)" and "aldehyde dehydrogenase 2 (ALDH2)" genes involved in alcohol metabolism. In this exercise, two different genotyping methods based on polymerase chain reaction (PCR), namely…

An organic chemistry experiment designed for senior undergraduates focuses on bifunctional catalysis, a critical yet often omitted topic at the undergraduate level, but essential for advanced studies in chemistry. By utilization of a tertiary amine-thiourea catalyst in the asymmetric Michael addition reaction, the experiment showcases the…

The turn to 'evidence-based education' in the past three decades favours one type of evidence: experiment. Knowledge brokers ground recommendations for classroom practice on reports of experimental research. This paper distinguishes "field" and "laboratory" experiments, on the basis of control and precision of causal…

Synthesis of (Z)-alkenes is challenging because the (E) stereoisomers are usually more stable. Energy transfer photocatalysis has emerged as an efficient strategy for (E) [right arrow] (Z) alkene isomerization. We report the development of an advanced undergraduate laboratory experiment that introduces students to contemporary organic…

Artificial intelligence (AI) and data science (DS) are receiving a lot of attention in various fields. In the educational field, the need for education utilizing AI and DS is also being emerged. In this context, we have created an AI/DS integrating program that generates a compound classification/regression model using characteristics of compounds…

The bromination of six isomeric alcohols is adapted to a discovery-based organic chemistry laboratory experiment, whereby students are provided an alcohol starting material and are charged with determining the product or product mixture produced using relevant spectroscopic data. The experiment solidifies NMR analysis skills while reinforcing the…

We have developed a new foundation-level course at our institution that links the concept of chemical equilibria from four of the traditional subdisciplines (analytical, biochemistry, inorganic, and physical). The course, entitled Solution and Solid State Chemistry (CHEM 210), is designed to serve our chemistry and biochemistry majors, as well as…

This laboratory experiment introduces upper-division undergraduate analytical chemistry students to liquid chromatography-tandem mass spectrometry (LC-MS/MS) in a forensic application: the analysis of cocaine and metabolites of cocaine in simulated serum ostensibly from drug overdose victims. For this investigation, students developed the…

We propose an apparatus that emulates the experiment used by Geiger and Marsden in 1913 to investigate alpha particles (Rutherford) scattering. Using a widely available fused deposition modelling 3D-printer, we built a compartmented and easily assembled educational instrument. The whole apparatus is composed of a 3D-printed chamber and an…