When randomized control trials are not possible, quasi-experimental methods often represent the gold standard. One quasi-experimental method is difference-in-difference (DiD), which compares changes in outcomes before and after treatment across groups to estimate a causal effect. DiD researchers often use fairly exhaustive robustness checks to…

Background: Randomized controlled trials (RCTs), or experiments, are the gold standard for intervention evaluation. However, the main appeal of RCTs--the clean identification of causal effects--can be compromised by interference, when one subject's actions can influence another subject's behavior or outcomes. In this paper, we formalize and study…

Background: As people with Parkinson's experience progressive communication changes, effective, implementable speech and language therapy (SLT) interventions are needed. Process evaluations alongside pragmatic randomised controlled trials (RCTs) are of clinical value if they describe, compare and understand the implementation of trial…

Background: Education scientists are increasingly interested in constructing interventions that are adaptive over time to suit the evolving needs of students, classrooms, or schools. Such "adaptive interventions" (also referred to as dynamic treatment regimens or dynamic instructional regimes) determine which treatment should be offered…

Cluster randomized trials (CRTs) are commonly used to evaluate the causal effects of educational interventions, where the entire clusters (e.g., schools) are randomly assigned to treatment or control conditions. This study introduces statistical methods for designing and analyzing two-level (e.g., students nested within schools) and three-level…

Background: Despite many adolescents experiencing mental health concerns, a substantial portion lack access to evidence-based treatments (EBTs) for psychopathology; this issue is magnified for adolescents belonging to communities considered marginalized. One way to ameliorate this is by adapting existent EBTs--typically delivered in research…

Individual participant data (IPD) meta-analysis projects obtain, harmonise, and synthesise original data from multiple studies. Many IPD meta-analyses of randomised trials are initiated to identify treatment effect modifiers at the individual level, thus requiring statistical modelling of interactions between treatment effect and participant-level…

Random encouragement designs are randomized controlled trials (RCTs) that test interventions aimed at increasing participation in a program or activity whose take up is not universal. In these RCTs, instead of randomizing individuals or clusters directly into treatment and control groups to participate in a program or activity, the randomization…

Although there is robust evidence of the benefits of attachment-based parenting interventions, limited research has examined their impact on dyadic mutuality and toddler behavior problems. Given the central question in prevention research of what works for whom, and the documented relation of maternal psychological risk to parenting and…

Purpose: This study aimed to investigate the effects of a self-paced digital working memory (WM) intervention on preschoolers with ADHD symptoms and explore the relation between WM and time perception (TP) through a randomized controlled trial. Method: Fifty preschoolers between four-to-six years of age (M = 4.93 years) were randomly assigned to…

Longitudinal randomized controlled trials generally assign individuals randomly to interventions at baseline and then evaluate how differential average treatment effects evolve over time. This study shows that longitudinal settings could benefit from "Recurrent Individual Treatment Assignment" ("RITA") instead, particularly in…

Evidence-based medicine (EBM) is helpful for laypersons' decision-making. This study aimed to evaluate the effectiveness of e-learning materials on the essential components of EBM for laypersons. We conducted a web-based, open-label, randomized controlled trial with laypersons in Japan aged [greater than or equal to]20 years who used the internet.…

Researchers and policymakers aspire for educational interventions to change children's long-run developmental trajectories. However, intervention impacts on cognitive and achievement measures commonly fade over time. Less is known, although much is theorized, about social-emotional skill persistence. The current meta-analysis investigated whether…

Sleep disturbances are one of the most common comorbidities in autistic children and adolescence. Considering the impact of sleep disorders on development and daily functioning, it is important to know which treatments are considered effective in literature. This systematic review and meta-analysis study specifically aimed to investigate the…

Understanding the factors associated with variation in the implementation of educational programs has emerged as a key research focus, in an effort to identify how promising programs can be scaled up across their targeted contexts. The current study explored demographic-related variation in program dosage using a novel source of implementation…