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Andrija Babic; Ognjen Barcot; Tomislav Viskovic; Frano Šaric; Aleksandar Kirkovski; Ivana Barun; Zvonimir Križanac; Roshan Arjun Ananda; Yuli Viviana Fuentes Barreiro; Narges Malih; Daiana Anne-Marie Dimcea; Josipa Ordulj; Ishanka Weerasekara; Matteo Spezia; Marija Franka Žuljevic; Jelena Šuto; Luca Tancredi; Andela Pijuk; Susanna Sammali; Veronica Iascone; Thilo Groote; Tina Poklepovic Pericic; Livia Puljak – Research Synthesis Methods, 2024
Risk of bias (RoB) assessment is essential to the systematic review methodology. The new version of the Cochrane RoB tool for randomized trials (RoB 2) was published in 2019 to address limitations identified since the first version of the tool was published in 2008 and to increase the reliability of assessments. This study analyzed the frequency…
Descriptors: Risk, Bias, Use Studies, Meta Analysis
Nejstgaard, Camilla Hansen; Laursen, David Ruben Teindl; Lundh, Andreas; Hróbjartsson, Asbjørn – Research Synthesis Methods, 2023
We investigated to which degree commercial funding is associated with estimated intervention effects in randomized trials. We included meta-epidemiological studies with published data on the association between commercial funding and results or conclusions of randomized trials. We searched five databases and other sources. We selected one result…
Descriptors: Private Financial Support, Intervention, Randomized Controlled Trials, Literature Reviews
Miriam Hattle; Joie Ensor; Katie Scandrett; Marienke van Middelkoop; Danielle A. van der Windt; Melanie A. Holden; Richard D. Riley – Research Synthesis Methods, 2024
Individual participant data (IPD) meta-analysis projects obtain, harmonise, and synthesise original data from multiple studies. Many IPD meta-analyses of randomised trials are initiated to identify treatment effect modifiers at the individual level, thus requiring statistical modelling of interactions between treatment effect and participant-level…
Descriptors: Meta Analysis, Randomized Controlled Trials, Outcomes of Treatment, Evaluation Methods
Emma R. Hart; Drew H. Bailey; Sha Luo; Pritha Sengupta; Tyler W. Watts – Annenberg Institute for School Reform at Brown University, 2024
Researchers and policymakers aspire for educational interventions to change children's long-run developmental trajectories. However, intervention impacts on cognitive and achievement measures commonly fade over time. Less is known, although much is theorized, about social-emotional skill persistence. The current meta-analysis investigated whether…
Descriptors: Literature Reviews, Meta Analysis, Children, Adolescents
Sandra Jo Wilson; Brian Freeman; E. C. Hedberg – Grantee Submission, 2024
As reporting of effect sizes in evaluation studies has proliferated, researchers and consumers of research need tools for interpreting or benchmarking the magnitude of those effect sizes that are relevant to the intervention, target population, and outcome measure being considered. Similarly, researchers planning education studies with social and…
Descriptors: Benchmarking, Effect Size, Meta Analysis, Statistical Analysis
Mindy L. Rosengarten; Emma R. Hart; Drew H. Bailey; Meghan P. McCormick; Benjamin J. Lovett; Tyler W. Watts – Annenberg Institute for School Reform at Brown University, 2024
Recent reviews of the educational intervention literature have noted patterns of intervention impact fadeout on cognitive skills, whereby skill trajectories between children in the intervention and control group converge in the years following the end of the intervention. Some early childhood education (ECE) researchers have suggested that skill…
Descriptors: Data Analysis, Meta Analysis, Intervention, Persistence
Deborah M. Caldwell; Jennifer C. Palmer; Katie E. Webster; Sarah R. Davies; Hugo Hughes; Joseph Rona; Rachel Churchill; Sarah E. Hetrick; Nicky J. Welton – Prevention Science, 2025
Many randomized controlled trials have investigated the role of school-based prevention interventions to reduce symptoms of anxiety and depression in young people. Systematic reviews have subsequently demonstrated a small, beneficial effect of these interventions when compared to a combined control group including usual care, no intervention, or…
Descriptors: Depression (Psychology), Prevention, Randomized Controlled Trials, Symptoms (Individual Disorders)
Nejstgaard, Camilla Hansen; Lundh, Andreas; Abdi, Suhayb; Clayton, Gemma; Gelle, Mustafe Hassan Adan; Laursen, David Ruben Teindl; Olorisade, Babatunde Kazeem; Savovic, Jelena; Hróbjartsson, Asbjørn – Research Synthesis Methods, 2022
Randomised trials are often funded by commercial companies and methodological studies support a widely held suspicion that commercial funding may influence trial results and conclusions. However, these studies often have a risk of confounding and reporting bias. The risk of confounding is markedly reduced in meta-epidemiological studies that…
Descriptors: Medical Research, Randomized Controlled Trials, Corporations, Financial Support
Cope, Shannon; Chan, Keith; Jansen, Jeroen P. – Research Synthesis Methods, 2020
Background: Network meta-analysis (NMA) of survival data with a multidimensional treatment effect has been introduced as an alternative to NMA based on the proportional hazards assumption. However, these flexible models have some limitations, such as the use of an approximate likelihood based on discrete hazards, rather than a likelihood for…
Descriptors: Multivariate Analysis, Meta Analysis, Network Analysis, Models
Sini Li; Yijing Yong; Yamin Li; Jianhe Li; Jiao Xie – Journal of Autism and Developmental Disorders, 2024
This review aims to systematically summarize existing evidence to determine the effectiveness of cognitive-based interventions (CBIs) on psychological health and well-being among parents of children with developmental disabilities (DD). Six databases were searched to identify eligible randomized controlled trials (RCTs) from their inception to…
Descriptors: Parents, Children, Developmental Disabilities, Metacognition
de Jong, Valentijn M. T.; Moons, Karel G. M.; Riley, Richard D.; Tudur Smith, Catrin; Marson, Anthony G.; Eijkemans, Marinus J. C.; Debray, Thomas P. A. – Research Synthesis Methods, 2020
Many randomized trials evaluate an intervention effect on time-to-event outcomes. Individual participant data (IPD) from such trials can be obtained and combined in a so-called IPD meta-analysis (IPD-MA), to summarize the overall intervention effect. We performed a narrative literature review to provide an overview of methods for conducting an…
Descriptors: Meta Analysis, Intervention, Randomized Controlled Trials, Guidelines
Moustgaard, Helene; Jones, Hayley E.; Savovic, Jelena; Clayton, Gemma L.; Sterne, Jonathan AC; Higgins, Julian PT; Hróbjartsson, Asbjørn – Research Synthesis Methods, 2020
Randomized clinical trials underpin evidence-based clinical practice, but flaws in their conduct may lead to biased estimates of intervention effects and hence invalid treatment recommendations. The main approach to the empirical study of bias is to collate a number of meta-analyses and, within each, compare the results of trials with and without…
Descriptors: Epidemiology, Evidence, Medical Research, Intervention
Martyn-St. James, Marrissa; Cooper, Katy; Kaltenthaler, Eva – Evidence & Policy: A Journal of Research, Debate and Practice, 2017
The aim of this study was to evaluate a rapid systematic review method in which randomised controlled trial (RCT) data was extracted from existing reviews and subsequent RCTs. The method enabled: identification of RCTs not included by existing reviews; cross-checking RCT data for consistency where there was more than one review; double data…
Descriptors: Randomized Controlled Trials, Research Methodology, Meta Analysis, Sexuality
Citkowicz, Martyna; Lindsay, Jim; Miller, David; Williams, Ryan – Society for Research on Educational Effectiveness, 2020
Many public and private initiatives have focused on improving prekindergarten (PK) through Grade 12 mathematics education, given that the mathematics content learned before college is foundational for later learning and college success across STEM subjects. Although decades of educational research have studied PK-12 mathematics interventions, the…
Descriptors: Intervention, Mathematics Instruction, Meta Analysis, Comparative Analysis
Demack, Sean; Maxwell, Bronwen; Coldwell, Mike; Stevens, Anna; Wolstenholme, Claire; Reaney-Wood, Sarah; Stiell, Bernadette; Lortie-Forgues, Hugues – Education Endowment Foundation, 2021
This report presents findings from exploratory, descriptive meta-analyses of effect sizes reported by the first 82 EEF evaluations that used a randomised controlled trial (RCT) or clustered RCT impact evaluation design published up to January 2019. The review used a theoretical framework derived from literature with five overarching themes to…
Descriptors: Foreign Countries, Disadvantaged Youth, Meta Analysis, Effect Size