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Showing all 9 results Save | Export
One Size Does Not Fit All for Parent-Mediated Autism Interventions: A Randomized Clinical Trial
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Roberts, Megan Y.; Sone, Bailey J.; Jones, Maranda; Grauzer, Jeffrey; Sudec, Laura; Stern, Yael S.; Kwok, Elaine; Losh, Molly; Kaat, Aaron – Autism: The International Journal of Research and Practice, 2023
Coaching parents to use language facilitation strategies improves long-term language outcomes for autistic children. To optimize parent-mediated interventions, more studies need to explore factors that influence parents' learning. This study involved 119 autistic children (18-48 months) and their biological mothers enrolled in a single-site,…
Descriptors: Autism Spectrum Disorders, Parent Participation, Intervention, Randomized Controlled Trials
What Are We Targeting When We Treat Autism Spectrum Disorder? A Systematic Review of 406 Clinical Trials
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Provenzani, Umberto; Fusar-Poli, Laura; Brondino, Natascia; Damiani, Stefano; Vercesi, Marco; Meyer, Nicholas; Rocchetti, Matteo; Politi, Pierluigi – Autism: The International Journal of Research and Practice, 2020
The number of trials aimed at evaluating treatments for autism spectrum disorder has been increasing progressively. However, it is not clear which outcome measures should be used to assess their efficacy, especially for treatments which target core symptoms. The present review aimed to provide a comprehensive overview regarding the outcome…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Outcome Measures
Efficacy and Safety of Memantine in Children with Autism Spectrum Disorder: Results from Three Phase 2 Multicenter Studies
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Hardan, Antonio Y.; Hendren, Robert L.; Aman, Michael G.; Robb, Adelaide; Melmed, Raun D.; Andersen, Kristen A.; Luchini, Rachel; Rahman, Rezwanur; Ali, Sanjida; Jia, X Daniel; Mallick, Madhuja; Lateiner, Jordan E.; Palmer, Robert H.; Graham, Stephen M. – Autism: The International Journal of Research and Practice, 2019
Three phase 2 trials were conducted to assess the efficacy and long-term safety of weight-based memantine extended release (ER) treatment in children with autism spectrum disorder. MEM-MD-91, a 50-week open-label trial, identified memantine extended-release treatment responders for enrollment into MEM-MD-68, a 12-week randomized, double-blind,…
Descriptors: Children, Autism, Pervasive Developmental Disorders, Drug Therapy
The Feasibility of Low-Intensity Psychological Therapy for Depression Co-Occurring with Autism in Adults: The Autism Depression Trial (ADEPT) -- A Pilot Randomised Controlled Trial
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Russell, Ailsa; Gaunt, Daisy M.; Cooper, Kate; Barton, Stephen; Horwood, Jeremy; Kessler, David; Metcalfe, Chris; Ensum, Ian; Ingham, Barry; Parr, Jeremy R.; Rai, Dheeraj; Wiles, Nicola – Autism: The International Journal of Research and Practice, 2020
Low-intensity cognitive behaviour therapy including behavioural activation is an evidence-based treatment for depression, a condition frequently co-occurring with autism. The feasibility of adapting low-intensity cognitive behaviour therapy for depression to meet the needs of autistic adults via a randomised controlled trial was investigated. The…
Descriptors: Depression (Psychology), Adults, Autism, Pervasive Developmental Disorders
Pebbles, Rocks, and Boulders: The Implementation of a School-Based Social Engagement Intervention for Children with Autism
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Locke, Jill; Wolk, Courtney Benjamin; Harker, Colleen; Olsen, Anne; Shingledecker, Travis; Barg, Frances; Mandell, David; Beidas, Rinad – Autism: The International Journal of Research and Practice, 2017
Few evidence-based practices, defined as the use of empirically supported research and clinical expertise for children with autism, have been successfully implemented and sustained in schools. This study examined the perspectives of school personnel (n = 39) on implementing a social engagement intervention for children with autism. Semi-structured…
Descriptors: Autism, Evidence Based Practice, Semi Structured Interviews, Administrators
Effects of an Employer-Based Intervention on Employment Outcomes for Youth with Significant Support Needs Due to Autism
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Wehman, Paul; Schall, Carol M.; McDonough, Jennifer; Graham, Carolyn; Brooke, Valerie; Riehle, J. Erin; Brooke, Alissa; Ham, Whitney; Lau, Stephanie; Allen, Jaclyn; Avellone, Lauren – Autism: The International Journal of Research and Practice, 2017
The purpose of this study was to develop and investigate an employer-based 9-month intervention for high school youth with autism spectrum disorder to learn job skills and acquire employment. The intervention modified a program titled Project SEARCH and incorporated the use of applied behavior analysis to develop Project SEARCH plus Autism…
Descriptors: Autism, Pervasive Developmental Disorders, High School Students, Intervention
The Relationship between Treatment Attendance, Adherence, and Outcome in a Caregiver-Mediated Intervention for Low-Resourced Families of Young Children with Autism Spectrum Disorder
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Carr, Themba; Shih, Wendy; Lawton, Kathy; Lord, Catherine; King, Bryan; Kasari, Connie – Autism: The International Journal of Research and Practice, 2016
Rates of participation in intervention research have not been extensively studied within autism spectrum disorder. Such research is important given the benefit of early intervention on long-term prognosis for children with autism spectrum disorder. The goals of this study were to examine how family demographic factors predicted treatment…
Descriptors: Autism, Pervasive Developmental Disorders, Outcomes of Treatment, Attendance
Meta-Analysis of Parent-Mediated Interventions for Young Children with Autism Spectrum Disorder
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Nevill, Rose E.; Lecavalier, Luc; Stratis, Elizabeth A. – Autism: The International Journal of Research and Practice, 2018
A number of studies of parent-mediated interventions in autism spectrum disorder have been published in the last 15 years. We reviewed 19 randomized clinical trials of parent-mediated interventions for children with autism spectrum disorder between the ages of 1 and 6 years and conducted a meta-analysis on their efficacy. Meta-analysis outcomes…
Descriptors: Meta Analysis, Intervention, Autism, Randomized Controlled Trials
Easing the Transition to Secondary Education for Children with Autism Spectrum Disorder: An Evaluation of the Systemic Transition in Education Programme for Autism Spectrum Disorder (STEP-ASD)
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Mandy, William; Murin, Marianna; Baykaner, Ozlem; Staunton, Sara; Cobb, Robert; Hellriegel, Josselyn; Anderson, Seonaid; Skuse, David – Autism: The International Journal of Research and Practice, 2016
In mainstream education, the transition from primary to secondary school ("school transition") is difficult for children with autism spectrum disorder, being marked by high levels of emotional and behavioural difficulties. The Systemic Transition in Education Programme for Autism Spectrum Disorder (STEP-ASD) is a new, manualised school…
Descriptors: Secondary Education, Children, Pervasive Developmental Disorders, Intervention