The rapid advances of information and communication technology (ICT) have transformed teaching and learning in universities. This study therefore sort to establish antecedents of university lecturers' intention to adopt ICT adoption in Zimbabwean universities. It employed a quantitative approach which used a structured questionnaire on a sample of 600 university lecturers from 6 selected public universities. Descriptive statistics and regression analysis were used for data analysis. Results of the study showed that policy support infrastructure (ICT policy, ICT policy implementation strategy and clear ICT vision), technical support infrastructure (competent support team, ICT tools and systems, internet and reliable power supply) and technical skills infrastructure (training and skills level) acted as antecedents to ICT adoption in Zimbabwean universities. A lack of ICT policy implementation plans and obsolete ICT infrastructure acted as major barriers to ICT adoption. These results have managerial and operational implications for universities to consider for effective adoption of ICT.