Purpose: This case series documents developmental changes over time and in response to a novel intervention, Sitting Together and Reaching to Play (START-Play), in children with early-life seizures. Methods: Thirteen children with early-life seizures were included from a subset of participants in the START-Play multisite, randomized controlled…

Sense enables babies to perceive the physical and chemical changes that occur in the external environment. It occurs as a result of the dynamic interaction of sensory stimuli with sensory receptors in the eyes, ears, tongue, nose, and skin. The stimuli that newborns see, touch, and hear affect their brain development. The brain develops faster in…

Dance is a universal human behavior and a crucial component of human musicality. When and how does the motivation and tendency to move to music develop? How does this behavior change as a process of maturation and learning? We characterize infants' earliest dance behavior, leveraging parents' extensive at-home observations of their children.…

This review describes a computational approach for modeling the development of speech motor control in infants. We address the development of two levels of control: articulation of individual speech sounds (defined here as phonemes, syllables, or words for which there is an optimized motor program) and production of sound sequences such as phrases…

A semistructured preschool motor program was developed in response to the paucity of evidence-based motor programs for preschoolers with disabilities in inclusive classrooms. A randomized controlled trial (RCT) was undertaken to examine the impact of the "CHildren in Action: Motor Program for PreschoolerS (CHAMPPS)," a 21-week…

Infancy is a period of significant change for both the brain and behavior. During the first two years of life, the brain experiences an explosion of synaptic connections and myelination, alongside rapid development in motor, linguistic, and social behavioral abilities. Understanding the relationship between brain development and behavioral…

Early childhood is a critical period characterized by rapid development of motor and language skills. Reliably assessing motor and language development in early childhood is difficult, and there is a lack of agreement on measurement tool use. This scoping review aims to identify measurement tools used to examine motor and language skills in…

The aim of our study is to describe the neuromotor development of preterm and low birth weight infants at 1 and 2 years of corrected age, and to examine the extent to which perinatal, neonatal, socio-demographic, and neuromotor development indices measured at the age of 1 are able to predict infants' development indices at the age of 2. Our sample…

Introduction: Down Syndrome (DS) is a common cause of intellectual disability with a possible glial-neuronal disruption. We assessed the effects of Cerebrolysin on the neurodevelopmental outcomes of infants with DS. Methods: This randomized controlled pilot trial included 64 infants with DS. They were allocated into a treatment group (n=32) who…

Exploration is considered essential to infant learning, but few studies have quantified infants' task exploration. The purpose of this study was to quantify how infants explored task space with their feet while learning to activate a kick-activated mobile. Data were analyzed from fifteen 4-month-old infants who participated in a 10-min mobile task…

Background: Spontaneous upper extremity movements in infancy provide insight on neuromotor development. Spatiotemporal kinematics have been used to evaluate typical development of reaching, a foundational motor skill in infancy. This study evaluates the relationship between spontaneous upper extremity movements, not elicited by a toy, and motor…

The objective of this study was to verify the effects on 4- to 18-month-old babies' NPMD after the family-centered Kids Intervention Therapy -- Aquatic Environment (KITE) programme. This quasi-experimental study involved 61 families. The NPMD was assessed with Alberta Infant Motor Scale (AIMS), Denver II Developmental Screening Test, context…

Autism is often associated with early developmental delays in language and motor skills. However, little is known about the complex dynamic processes that drive the co-development of such early difficulties. The aim of the present study was to model the parallel growth of language and motor skills in a cohort of infants and to explore differences…

Multiple domains develop simultaneously and interact throughout infancy and early childhood. Although relationships between motor and language skills have been examined cross-sectionally during the first three years of life, little is known regarding the individual factors that influence the development of these domains as well as the relationship…

Purpose: This study tested whether the Sitting Together and Reaching to Play (START-Play) physical therapy intervention indirectly impacts cognition through changes in perceptual-motor skills in infants with motor delays. Methods: Participants were 50 infants with motor delays randomly assigned to START-Play plus Usual Care Early Intervention…