Enzymes, enzymatic kinetics, and enzyme inhibition are topics covered in undergraduate biochemistry textbooks, having perceptible relevance to everyday life. The experimental use of enzymes involved in basic physiologic processes may be of utmost pedagogic interest because they bring evidence on how a significant number of drugs are used to…

Biopharmaceuticals are gaining high relevance in the pharmaceutical industry and market, due to their specific design for many therapeutic conditions and ability to restore biological functions. As a matter of fact, gene therapy products have been studied and developed in the past several years, and more recently, they arouse real interest as…

A collection of four activities for science outreach events was developed to teach middle school students about the temperature dependence of scientific phenomena. Procedures are described for four interactive demonstrations on phase changes, fluorescence, viscosity effects on diffusion, and conductivity. Each hands-on activity helps students…

Already when they enter primary school, children have rich everyday experience with factors influencing the rate of liquids' evaporation. Tea spilled into a large puddle on the table evaporates more rapidly than the same amount remaining in the cup, laundry hanging on a clothesline dries faster on a hot and windy day in comparison with a cold and…

An experiment for the upper-level biochemistry laboratory is described in which students isolate a wild yeast from environmental sources and characterize the strain for its potential in the brewing industry. In addition to providing valuable experience in important biochemical techniques, this study also illustrates key principles of…

This article describes two sets of experiments designed to enhance the understanding of colloidal systems. These experiments were designed as a part of the theme "Colloids: Where Science Meets Engineering" taught in the Department of Chemical Engineering and additionally offered to physics, chemistry, and materials science departments as…

Multistep synthesis is a key capstone experience in organic laboratory instruction. Here, a four-step synthesis of avobenzone, an active component in sunscreens, has been developed that can be completed in two 4 h laboratory periods. This synthesis incorporates green principles and includes an aldol condensation, electrophilic addition of bromine…

The possibility of conducting laboratory experiments at home without using commercially available kits, which might also be overly expensive, seems to be a suitable approach for a distance chemistry laboratory. Thus, several hands-on experiments with household supplies have been developed aiming at fostering students' laboratory competencies, as…

Over 200 years ago, Alessandro Volta published his observations of a steady voltage when a piece of electrolyte-soaked cardboard was sandwiched between two dissimilar metals. This observation initiated a century of argument as to the origin of voltaic electricity (contact vs chemical) and catalyzed practical advances, such as the first…

In this paper, we present a concise and technique-heavy route to the synthesis of dimedone for a second-year organic chemistry curriculum. Our preparation of dimedone guides students through a Michael addition followed by a Dieckmann cyclization, basic ester hydrolysis, and thermal decarboxylation, while allowing time for mechanistic discussion…

The synthesis of a [2]rotaxane through three- or five-component coupling reactions has been adapted to an organic chemistry experiment for upper-division students. The experimental procedure addresses the search for the most favorable reaction conditions for the synthesis of the interlocked compound, which is obtained in a yield of up to 71%.…

Metabolic Control Analysis (MCA) is a systems biology approach that measures the control of a metabolic step on the overall flux of a metabolic pathway. In undergraduate courses in biochemistry, learning of MCA can be encouraged by experimental activities demonstrating practical applications of the MCA theory. In this work, we present a laboratory…

Providing hands-on practical education without access to laboratories during the COVID-19 pandemic has required creativity and innovation. In this paper, co-authored by academic staff and students, we describe an at-home mobile phone-based 'spectrophotometer' experiment used in an introductory undergraduate biology course. Using colour picker…

Purpose: The aim of this research is to determine the impact of hands-on science activities on preschool children's motivation for science. Design/Approach/Methods: The study group of the research, in which the quasi-experimental design with pretest-posttest control group was used, consists of 25 children aged 60-72 months who are continuing their…

A multistep synthesis of a novel arylidene 3­(2"H")-furanone has been designed and optimized for the second-year organic laboratory. The three-step sequence consists of a nucleophilic substitution, intramolecular cyclization, and acid-catalyzed aldol condensation, and can be carried out within two 3 h laboratory periods. The final…