Until now, the conventional approach using two distinct groups, experimental and control, continues to dominate research, especially education research. Researchers, particularly those who are active in this domain, readily recognise this pattern when surveying literature. This article explores the use of the Solomon four-group design as a…

This article describes our efforts to screen and enrol clinical trial participants conscientiously in the COVID-19 pandemic setting. We present the standard screening and enrolment process prior to, and our process of adapting to, the pandemic. Our goal was to develop a way to screen and enrol people for clinical trials that was both equitable and…

Several branches of the potential outcome causal inference literature have discussed the merits of blocking versus complete randomization. Some have concluded it can never hurt the precision of estimates, and some have concluded it can hurt. In this article, we reconcile these apparently conflicting views, give a more thorough discussion of what…

Although most individuals experience expectation violations in their educational years, individuals' coping strategies differ depending on situational and dispositional characteristics with potentially decisive influence on educational outcomes. As a situational characteristic, optimism bias indicates that individuals tend to update their…

Existing systems for automating the assessment of risk-of-bias (RoB) in medical studies are supervised approaches that require substantial training data to work well. However, recent revisions to RoB guidelines have resulted in a scarcity of available training data. In this study, we investigate the effectiveness of generative large language…

Pregnancy is a frequently applied exclusion criteria for many forms of research. Common justifications for this exclusion include the potential for teratogenicity, as well as the potential for physiologic changes in pregnancy to impact the research itself. The systematic exclusion of pregnant persons from clinical studies has created a significant…

Strategy interventions have been found to support students' text comprehension, but little is known about the sustainability of these effects. This study examined short- and long-term effects of a strategy intervention on students' vocabulary and text comprehension at the literal, inferential and evaluative levels. A pretest, posttest, and…

Developmental disabilities (DD) research has depended on volunteer and clinical samples, with limited racial/ethnic diversity. This study focused on improving diversity and retention in DD research. The sample included 225 parents with a child with DD and 4,002 parents without children with DD from diverse racial/ethnic groups, drawn from Midlife…

Tuberous sclerosis complex (TSC) is a genetic condition characterized by both medical and neuropsychiatric diagnoses that emerge across the lifespan. As part of a clinical trial, caregivers of children with TSC were interviewed about their experiences navigating medical, school, and social services. Semistructured interviews (N = 20) with…

Systematic reviewers are advised to search trials registers to minimise risk of reporting biases. However, there has been little research on the impact of searching trials registers on the results of meta-analyses. We aimed to evaluate the impact of searching clinical trials registers for systematic reviews of pharmaceutical or non-pharmaceutical…

Searching for trials is a key task in systematic reviews and a focus of automation. Previous approaches required knowing examples of relevant trials in advance, and most methods are focused on published trial articles. To complement existing tools, we compared methods for finding relevant trial registrations given a International Prospective…

In health technology assessment, matching-adjusted indirect comparison (MAIC) is the most common method for pairwise comparisons that control for imbalances in baseline characteristics across trials. One of the primary challenges in MAIC is the need to properly account for the additional uncertainty introduced by the matching process. Limited…

Background: In the modern music industry, AI music generators have gained particular importance. The use of AI greatly simplifies the creation of polyphony. In addition, it can increase student motivation and interest. Aims: This study focuses on the AI-assisted creation of polyphonic music. The purpose of this study is to determine how creating…

Stem cell therapy, a cutting-edge technology, aims to replace damaged cells with healthy ones. Stem cells possess the remarkable ability to multiply and differentiate into various cell types, making them ideal candidates for regenerative medicine. This therapy holds promise for treating a wide range of conditions and injuries. In this review, I…

Many interventions in education occur in settings where treatments are applied to groups. For example, a reading intervention may be implemented for all students in some schools and withheld from students in other schools. When such treatments are nonrandomly allocated, outcomes across the treated and control groups may differ due to the treatment…