Using spatial mapping processes to discriminate between threat and safety is crucial for survival. Little is known why some fail to discriminate during contextual conditioning. We used a virtual reality (VR) contextual conditioning paradigm to elucidate the effects of state and trait anxiety on contextual threat learning. Participants (n = 70)…

Distinguishing safety from danger is necessary for survival, but is aberrant in individuals with post-traumatic stress disorder (PTSD). While PTSD is more prevalent in women than men, research on sex differences in safety learning is limited. Here, female rats demonstrated greater fear discrimination than males in a CS+/CS- paradigm. To determine…

Generalization of fear can involve abnormal responding to cues that signal safety and is common in people diagnosed with post-traumatic stress disorder. Differential auditory fear conditioning can be used as a tool to measure changes in fear discrimination and generalization. Most prior work in this area has focused on elevated amygdala activity…

Individuals with anxiety disorders often do not respond to safety signals and hence continue to be afraid and anxious. Consequently, it is important to develop paradigms in animals that can directly study brain systems involved in learning about, and responding to, safety signals. We previously developed a discrimination procedure in rats of the…

The purpose of this study was to analyze fear extinction and reinstatement in humans using fear-potentiated startle. Participants were fear conditioned using a simple discrimination procedure with colored lights as the conditioned stimuli (CSs) and an airblast to the throat as the unconditioned stimulus (US). Participants were extinguished 24 h…

Examined seven-month-old infants' perceptions of happy and fearful facial expressions. Infants could generalize discrimination of expressions across male and female faces if first familiarized with happy faces. Infants tended to look longer at fear faces than at happy faces. Preferential responding was not specific to any individual face.…

Three experiments investigated seven-month-old infants' ability to discriminate the facial expressions of happiness and fear. (CM)

Reviews research which demonstrates that responses from different behavior systems to a given stimulus situation may be far from perfectly correlated with each other. Discusses the phylogenetic and ontogenetic development of these systems and the roles of both the species and the individual in bringing the systems into mutual correspondence.…

Facial configuration and height were systematically varied as four different strangers--a male and female child, a female adult and a small female adult (midget)--each approached 40 different infants. The infants responded as if there were 3 classes of persons, suggesting that both size and facial configuration cues were used. (Author/SB)

The neural mechanisms of fear suppression most commonly are studied through the use of extinction, a behavioral procedure in which a feared stimulus (i.e., one previously paired with shock) is nonreinforced repeatedly, leading to a reduction or elimination of the fear response. Although extinction is perhaps the most convenient index of fear…

The present study was aimed at simultaneously determining on the same subject, the effects of stress on retrieval of flexible (contextual or temporal) or stable (spatial) information. Three behavioral paradigms carried out in a four-hole board were designed as follows: (1) Simple Discrimination (SD), in which mice learned a single discrimination;…

Two experiments assessed recognition of emotion among physically abused and neglected preschoolers. Results showed that neglected children had more difficulty discriminating emotional expressions that control or abused children. Abused children displayed response bias for angry facial expressions. Control children viewed discrete emotions as…