Rare events meta-analyses of randomized controlled trials (RCTs) are often underpowered because the outcomes are infrequent. Real-world evidence (RWE) from non-randomized studies may provide valuable complementary evidence about the effects of rare events, and there is growing interest in including such evidence in the decision-making process.…

Bayesian statistical methods have become more feasible to implement with advances in computing but are not commonly used in educational research. In contrast to frequentist approaches that take hypotheses (and the associated parameters) as fixed, Bayesian methods take data as fixed and hypotheses as random. This difference means that Bayesian…