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Direct linkVazquez, Maribel; Frazier, Jessica H.; Reichel, Carmela M.; Peters, Jamie – Learning & Memory, 2020
Females are at higher risk for certain opioid addictive behaviors, but the influence of ovarian hormones is unknown. In our rat model of heroin self-administration, females exhibited higher relapse rates that correlated with rates of heroin seeking on the first extinction session. We administered estradiol alone, or in combination with…
Descriptors: Females, Narcotics, Addictive Behavior, Biochemistry
